Characterization of Protein Complexes and Subcomplexes in Protein-Protein Interaction Databases

Figure 3

Representation and visualization methods of nested complexes. (a) Maximal complex, hiding nesting. (b) Multiedge representation. (c) Multihub representation. (d) Multinode representation. (e) Node-attribute representation. The multiedge view keeps one node per protein and represents every different complex with a different edge color. The multihub view splits the hub of the complex into three different nodes, one for each complex. The multinode just generates three separated complexes (distinct nodes and edges in the same graph). The node-attribute view uses single edges and, here, stores the information on complex membership as a pie for each node.

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