Changes in Lipid Profiles of HIV+ Adults over Nine Months at a Harare HIV Clinic: A Longitudinal Study
Table 4
Comparison of patients with dyslipidemia at baseline and follow-up.
Baseline
ART history
Type of dyslipidemia
ART naïve ()
ART experienced ()
Total ()
Elevated TC/ (%)
1 (4.4%)
55 (37.2%)
56 (32.8%)
0.020
Depressed HDL/ (%)
17 (73.9%)
77 (52.0%)
94 (55.0%)
0.050
Elevated LDL/ (%)
5 (21.7%)
34 (23.0%)
39 (22.8%)
0.896
Elevated TC/HDL ratio/ (%)
6 (26.1%)
35 (23.7%)
41 (24.0%)
0.799
Dyslipidemia/ (%)
19 (82.6%)
117 (79.1%)
136 (79.5%)
0.694
Nine-month follow-up
ART history
Type of dyslipidemia
ART naïve ()
ART experienced ()
Total ()
Elevated TC/ (%)
0 (0%)
23 (15.9%)
23 (13.7%)
0.040
Depressed HDL/ (%)
9 (39.1%)
69 (46.6%)
78 (45.6%)
0.502
Elevated LDL/ (%)
2 (34.8%)
30 (20.3%)
38 (22.2%)
0.119
Elevated TC/HDL ratio/ (%)
2 (88.70%)
17 (11.6%)
19 (11.2%)
0.685
Dyslipidemia/ (%)
14 (60.9%)
96 (64.9%)
110 (64.3%)
0.710
Note: SD: Standard deviation; level of significance is set at ; from -test comparison of means; from McNemar chi square tests for paired data by time of visit; cutoff values according to NCEP guidelines [20]: elevated TC > 5.2 mmol/L, depressed HDL < 1.1 mmol/L, elevated LDL > 3.2 mmol/L, and elevated TC/HDL ratio > 4.5.
