Research Article
Novel 4-Thiazolidinone Derivatives as Anti-Infective Agents: Synthesis, Characterization, and Antimicrobial Evaluation
Table 3
Values of the minimum inhibitory concentration of the synthesized compounds and reference standards.
| S. number | Microbial strains | MIC of compounds (µg/mL) | 4a | 4b | 4c | 4d | 4e | 4f | N | F |
| 1 | Staphylococcus aureus | 300 | 500 | 300 | 400 | 400 | 300 | 2.5 | — | 2 | Bacillus subtilis | 300 | 200 | 400 | 300 | 300 | 100 | 5 | — | 3 | Bacillus pumilus | 300 | 100 | 300 | 100 | 200 | 500 | 1.25 | — | 4 | Micrococcus luteus | 300 | 500 | 500 | 300 | 300 | 300 | — | — | 5 | Pseudomonas aeruginosa | 200 | 300 | 300 | 300 | 400 | 400 | 2.5 | — | 6 | Pseudomonas fluorescens | 100 | 100 | 300 | 100 | 200 | 300 | 2.5 | — | 7 | Escherichia coli | 300 | 100 | 300 | 400 | 400 | 200 | 2.5 | — | 8 | Aspergillus niger | 300 | 100 | 100 | 100 | 300 | 300 | — | 2.5 | 9 | Penicillium chrysogenum | 400 | 100 | 100 | 100 | 300 | 300 | — | 1.25 |
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N: norfloxacin and F: fluconazole.
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