Table 4: Effect of naringenin oxime (NOX) on serum liver enzymes, renal function markers, myeloperoxidase (MPO), and ceruloplasmin (CERP) of cisplatin induced rat.

BUN (mg/dl)Cre (mg/dl)ALT (U/L)AST (U/L)MPO (U/g)CERP

Control38,69 ± 6,0,28 ± 0,035,4 ± 6,73,3 ± 4,127,2 ± 1,6599,9 ± 41,1
Cis64,11 ± 5,0,60 ± 0,067,3 ± 8,144,2 ± 9,130 ± 2,8666,9 ± 86,6
Cis + NOX2055,67 ± 5,0,46 ± 0,052,6 ± 9,105,3 ± 18,28,8 ± 2,8601,6 ± 95,4
Cis + NOX4047,30 ± 4,0,38 ± 0,042,9 ± 8,86,7 ± 12,28 ± 5,6624,0 ± 30,7
NOX2037,81 ± 6,0,30 ± 0,037,2 ± 6,73,5 ± 10,24,4 ± 4597,4 ± 183,0
value0,0000,0000,0000,0000,6000,685

Values are given as the means ± SD. There were no significant differences between the cis and control groups in terms of any parameter (). , compared with the control group. , groups in which Cis and NOX are treated together compared with the Cis group.