Table of Contents Author Guidelines Submit a Manuscript
Biochemistry Research International
Volume 2018, Article ID 1467143, 6 pages
https://doi.org/10.1155/2018/1467143
Research Article

Influences of Oldenlandia diffusa on the CYP450 Activities in Rats Using a Cocktail Method by UHPLC-MS/MS

1Department of Pharmacology, Jinhua Polytechnic, Zhejiang, China
2Central Hospital of Jinhua, Zhejiang, China

Correspondence should be addressed to Yiping Lin; moc.qq@2914154242

Received 23 November 2017; Revised 30 January 2018; Accepted 27 February 2018; Published 3 April 2018

Academic Editor: Robert J. Linhardt

Copyright © 2018 Yiping Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. J. Kim, Y. G. Kim, D. S. Kim et al., “Oldenlandia diffusa ameliorates dextran sulphate sodium-induced colitis through inhibition of NF-kappab activation,” American Journal of Chinese Medicine, vol. 39, no. 5, pp. 957–969, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. T. Wajima, Y. Anzai, T. Yamada, H. Ikoshi, and N. Noguchi, “Oldenlandia diffusa extract inhibits biofilm formation by haemophilus influenzae clinical isolates,” PLoS One, vol. 11, no. 11, Article ID e0167335, 2016. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. H. Song, S. J. Jeong, H. Y. Kwon, B. Kim, S. H. Kim, and D. Y. Yoo, “Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells,” Biological and Pharmaceutical Bulletin, vol. 35, no. 7, pp. 1022–1028, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. H. S. Chung, H. J. Jeong, S. H. Hong et al., “Induction of nitric oxide synthase by Oldenlandia diffusa in mouse peritoneal macrophages,” Biological and Pharmaceutical Bulletin, vol. 25, no. 9, pp. 1142–1146, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. C. T. Ting, C. J. Kuo, H. Y. Hu, Y. L. Lee, and T. H. Tsai, “Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database,” BMC Complementary and Alternative Medicine, vol. 17, no. 1, p. 118, 2017. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Lee, J. H. Shim, H. Gim, H. S. Park, and B. J. Kim, “Ethanol extract of Oldenlandia diffusa-an effective chemotherapeutic for the treatment of colorectal cancer in humans: -anti-cancer effects of Oldenlandia diffusa,” Journal of Pharmacopuncture, vol. 19, no. 1, pp. 51–58, 2016. View at Publisher · View at Google Scholar · View at Scopus
  7. D. Bonofiglio, C. Giordano, F. De Amicis, M. Lanzino, and S. Ando, “Natural products as promising antitumoral agents in breast cancer: mechanisms of action and molecular targets,” Mini-Reviews in Medicinal Chemistry, vol. 16, no. 8, pp. 596–604, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. D. F. Lewis, “Human cytochromes P450 associated with the phase 1 metabolism of drugs and other xenobiotics: a compilation of substrates and inhibitors of the CYP1, CYP2 and CYP3 families,” Current Medicinal Chemistry, vol. 10, no. 19, pp. 1955–1972, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. H. Nishimuta, T. Nakagawa, N. Nomura, and M. Yabuki, “Species differences in hepatic and intestinal metabolic activities for 43 human cytochrome P450 substrates between humans and rats or dogs,” Xenobiotica, vol. 43, no. 11, pp. 948–955, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. O. Pelkonen, “Human CYPs: in vivo and clinical aspects,” Drug Metabolism Reviews, vol. 34, no. 1-2, pp. 37–46, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Rendic and F. J. Di Carlo, “Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors,” Drug Metabolism Reviews, vol. 29, no. 1-2, pp. 413–580, 1997. View at Publisher · View at Google Scholar
  12. D. F. Lewis, “P450 structures and oxidative metabolism of xenobiotics,” Pharmacogenomics, vol. 4, no. 4, pp. 387–395, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Geng, H. Si, D. Kang et al., “Influences of Re Du Ning Injection, a traditional Chinese medicine injection, on the CYP450 activities in rats using a cocktail method,” Journal of Ethnopharmacology, vol. 174, pp. 426–436, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. G. Li, K. Huang, D. Nikolic, and R. B. van Breemen, “High-throughput cytochrome p450 cocktail inhibition assay for assessing drug-drug and drug-botanical interactions,” Drug Metabolism and Disposition, vol. 43, no. 11, pp. 1670–1678, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Ingelman-Sundberg, “Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future,” Trends in Pharmacological Sciences, vol. 25, no. 4, pp. 193–200, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. D. D. Breimer and J. H. Schellens, “A ‘cocktail’ strategy to assess in vivo oxidative drug metabolism in humans,” Trends in Pharmacological Sciences, vol. 11, no. 6, pp. 223–225, 1990. View at Publisher · View at Google Scholar · View at Scopus
  17. W. Lin, J. Zhang, X. Ling et al., “Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC-DAD: a cocktail approach,” Journal of Chromatography B, vol. 923-924, pp. 29–36, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Rendic, “Summary of information on human CYP enzymes: human P450 metabolism data,” Drug Metabolism Reviews, vol. 34, no. 1-2, pp. 83–448, 2002. View at Publisher · View at Google Scholar · View at Scopus
  19. Q. Wu, Q. Zhang, C. Wen, L. Hu, X. Wang, and G. Lin, “The effect of MS-275 on CYP450 isoforms activity in rats by cocktail method,” International Journal of Clinical and Experimental Pathology, vol. 8, pp. 9360–9367, 2015. View at Google Scholar
  20. S. J. Kim, W. S. Chung, S. S. Kim, S. G. Ko, and J. Y. Um, “Antiinflammatory effect of Oldenlandia diffusa and its constituent, hentriacontane, through suppression of caspase-1 activation in mouse peritoneal macrophages,” Phytotherapy Research, vol. 25, no. 10, pp. 1537–1546, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. Kim, E. J. Park, J. Kim, Y. Kim, S. R. Kim, and Y. Y. Kim, “Neuroprotective constituents from Hedyotis diffusa,” Journal of Natural Products, vol. 64, no. 1, pp. 75–78, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. C. M. Lu, J. J. Yang, P. Y. Wang, and C. C. Lin, “A new acylated flavonol glycoside and antioxidant effects of Hedyotis diffusa,” Planta Medica, vol. 66, no. 4, pp. 374–377, 2000. View at Publisher · View at Google Scholar · View at Scopus