Leaf-Methanolic Extract of Pseudopanax arboreus (Araliaceae) (L. F. Phillipson) Reverses Amitriptyline-Induced Sexual Dysfunction in Male Rats

Table 3

Effects of the leaf-methanolic extract of P. arboreus (ME1 and ME2) on ejaculation latency (EL) (s) and postejaculatory interval (PEI) (s) of amitriptyline-induced sexually impaired male rats.

	Treatment
Parameter	Day	DW	Viagra	ME1	ME2
EL (s)	1	808.00 ± 120.78^ae	753.80 ± 12.13^be	648.40 ± 165.76^ce	755.80 ± 105.95^be
	7	648.40 ± 98.76^af	726.00 ± 25.64^be	735.20 ± 170.71^bf	491.60 ± 120.38^cf
	14	692.20 ± 110.30^af	735.20 ± 15.71^be	422.40 ± 171.83^cg	649.20 ± 106.83^ag
	21	858.20 ± 91.45^ae	703.40 ± 25.59^be	798.60 ± 180.02^ah	692.20 ± 120.30^cg
PEI (s)	1	421.20 ± 65.01^ae	369.00 ± 30.16^be	477.00 ± 20.99^ce	493.20 ± 80.98^ce
	7	477.80 ± 55.99^af	292.40 ± 28.00^be	443.40 ± 20.17^ae	443. 20 ± 75. 26^ae
	14	537.80 ± 70.51^ag	332.00 ± 35.59^be	413.40 ± 25.39^ce	359.60 ± 63.79^bf
	21	417.40 ± 60.38^ae	351.60 ± 30.02^be	437.40 ± 29.38^ae	332.00 ± 75.59^bf

Values presented as mean ± SEM; DW: distilled water; ME1: methanolic extract dose 1 (46.5 mg/kg); ME2: methanolic extract dose 2 (93 mg/kg); s: seconds; on the same row, values with same letters (a–c) are not significantly different; on the same row, values with different letters are significantly different; on the same column, values with the same letters (e–g) are not significantly different; on the same column, values with different letters are significantly different; EL: ejaculation latency (s); PEI: postejaculatory interval (s).