Research Article

Molecular Modeling of Antimalarial Agents by 3D-QSAR Study and Molecular Docking of Two Hybrids 4-Aminoquinoline-1,3,5-triazine and 4-Aminoquinoline-oxalamide Derivatives with the Receptor Protein in Its Both Wild and Mutant Types

Table 1

Chemical structures and activities of 4-aminoquinoline oxalamide and derivatives.

CompoundsStructure of compoundLog IC50 (observed)

11.958

21.496

32.367

41.701

51.500

61.915

71.405

82.368

91.193

101.422
112.418

121.611

131.902

141.927

152.130

161.623