Research Article

Molecular Modeling of Antimalarial Agents by 3D-QSAR Study and Molecular Docking of Two Hybrids 4-Aminoquinoline-1,3,5-triazine and 4-Aminoquinoline-oxalamide Derivatives with the Receptor Protein in Its Both Wild and Mutant Types

Table 2

Chemical structures and activities of the 4-aminoquinoline-triazine and derivatives.

CompoundsStructure of compoundLog IC50 (observed)

171.817

181.167

191.201

200.897
211.346

221.473

231.595

241.001
251.683

260.719

270.953

281.194

290.960
301.717

311.605

322.215

331.603

341.252