Research Article

Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection

Table 3

Top 10 GO functions of the cross-genes in the network.

CategoryGene termsCount value

Biological processGO:0003148, outflow tract septum morphogenesis101.24E − 09
GO:0003151, outflow tract morphogenesis153.98E − 09
GO:0001655, urogenital system development306.76E − 09
GO:0003279, cardiac septum development171.22E − 08
GO:0060411, cardiac septum morphogenesis131.60E − 07
GO:0010632, regulation of epithelial cell migration261.74E − 07
GO:0010631, epithelial cell migration291.75E − 07
GO:0061564, axon development331.77E − 07
GO:0043542, endothelial cell migration251.77E − 07
GO:0090132, epithelium migration292.09E − 07

Cellular componentGO:0005667, transcription factor complex234.28E − 07
GO:0097060, synaptic membrane269.71E − 06
GO:0045211, postsynaptic membrane212.70E − 05
GO:0099699, integral component of synaptic membrane143.31E − 05
GO:0005912, adherens junction287.12E − 05
GO:0099240, intrinsic component of synaptic membrane147.62E − 05
GO:0033267, axon part220.000108619
GO:0000790, nuclear chromatin200.000128584
GO:0099055, integral component of postsynaptic membrane110.000162968
GO:0000151, ubiquitin ligase complex160.000198327

Molecular functionGO:0000978, RNA polymerase II proximal promoter sequence-specific DNA binding385.75E − 10
GO:0000987, proximal promoter sequence-specific DNA binding395.92E − 10
GO:0035326, enhancer binding191.24E − 09
GO:0000980, RNA polymerase II distal enhancer sequence-specific DNA binding151.89E − 08
GO:0001158 enhancer sequence-specific DNA binding165.18E − 08
GO:0003682, chromatin binding349.92E − 08
GO:0001228, DNA-binding transcription activator activity, RNA polymerase II-specific292.20E − 06
GO:0004714, transmembrane receptor protein tyrosine kinase activity97.94E − 06
GO:0003712, transcription coregulator activity321.19E − 05
GO:0019199, transmembrane receptor protein kinase activity101.30E − 05