Biochemistry Research International

Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes


Publishing date
20 Jul 2012
Status
Published
Submission deadline
20 Jan 2012

1Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA

2Department of Basic Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan

3Department of Neurobiology, Physiology and Behavior, University of California, Oakland, CA, USA

4Department of Physiology and Biophysics, School of Medicine, Boston University, Boston, MA, USA


Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes

Description

Worldwide cardiovascular diseases (CVDs) are the leading cause of death with heart failure being highly prevalent in most affluent parts of the world. Despite significant clinical advances in the treatment of CVD, mortality rates remain high. Cardiomyopathy is a category of disorders that affects the cardiac muscle and can cause extensive disability in a large and ethnically diverse population. Cardiomyopathy has been classified by the World Health Organization into three main types, based on anatomical and physiological features: dilated (DCM), hypertrophic (HCM/FHC), and restrictive (RCM). It is becoming evident that the most promising approaches to alleviate or reverse detrimental disease phenotypes must emerge from target-specific interventions determined by the functional phenotype.

We invite authors to submit original research and review articles that seek to enhance the knowledge on cardiomyopathies, etiology, clinical, and functional phenotypes, as well as basic and translational research advances. Potential topics include, but are not limited to:

  • Genetics and genomics of cardiomyopathies: FHC, DCM, and RCM
  • Molecular and cellular mechanisms involved in cardiomyopathies
  • Progression to heart failure
  • Myofilament proteins: disease-causing mutations
  • Animal models of FHC, DCM, and RCM
  • Hypertrophic signaling pathways
  • Contractility and calcium handling
  • Energy consumption and metabolism
  • Imaging techniques
  • Cardiac regeneration, stem cells, and tissue engineering

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bcri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 870942
  • - Editorial

Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes

Danuta Szczesna-Cordary | Sachio Morimoto | ... | Jeffrey R. Moore
  • Special Issue
  • - Volume 2012
  • - Article ID 824068
  • - Research Article

Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics

Sampath K. Gollapudi | Murali Chandra
  • Special Issue
  • - Volume 2012
  • - Article ID 796926
  • - Review Article

Cardiomyopathy Classification: Ongoing Debate in the Genomics Era

Charles McCartan | Robert Mason | ... | Lyn R. Griffiths
  • Special Issue
  • - Volume 2012
  • - Article ID 639250
  • - Review Article

The Mutations Associated with Dilated Cardiomyopathy

Ruti Parvari | Aviva Levitas
  • Special Issue
  • - Volume 2012
  • - Article ID 715197
  • - Review Article

Application of Echocardiography on Transgenic Mice with Cardiomyopathies

G. Chen | Y. Li | ... | X. P. Huang
  • Special Issue
  • - Volume 2012
  • - Article ID 973723
  • - Review Article

In Search of Novel Targets for Heart Disease: Myocardin and Myocardin-Related Transcriptional Cofactors

Alexander T. Mikhailov | Mario Torrado
  • Special Issue
  • - Volume 2012
  • - Article ID 685108
  • - Research Article

A Novel Myosin Essential Light Chain Mutation Causes Hypertrophic Cardiomyopathy with Late Onset and Low Expressivity

Paal Skytt Andersen | Paula Louise Hedley | ... | Michael Christiansen
Biochemistry Research International
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