Human Coronary Artery Smooth Muscle Cell Responses to Bioactive Polyelectrolyte Multilayer Interfaces
Figure 1
Morphology of hCASMC cultures on PEMU surfaces after 24 hours on (a) uncoated glass, (b) (PFPVP/Nafion)2, (c) (PDADMA/PSS)2, and (d) (PAH/PAA-co-PAEDAPS)2. After 5 days, hCASMCs on (e) uncoated glass achieved a uniform, confluent layer, while cells on (f) (PFPVP/Nafion)2 exhibited a “hill and valley” morphology. Cells on (g) (PDADMA/PSS)2 exhibited continued aggregation with a pattern similar to that seen on (PFPVP/Nafion)2, but with less alignment of the cells. Cultures on (h) (PAH/PAA-co-PAEDAPS)2 were virtually unchanged after 5 days. All images are 100x. Scale bar = 20 μm.
