Table of Contents
Biotechnology Research International
Volume 2011, Article ID 857925, 6 pages
Research Article

Antibacterial Activities of Actinomycete Isolates Collected from Soils of Rajshahi, Bangladesh

1Department of Pharmacy, University of Rajshahi, Rajshahi 6205, Bangladesh
2Department of Parasitology, Aichi Medical University, Aichi-ken 480-1195, Japan
3Department of Biology, The Catholic University of America, Washington, DC 20064, USA

Received 23 April 2011; Accepted 26 May 2011

Academic Editor: Triantafyllos Roukas

Copyright © 2011 Md. Ajijur Rahman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study was performed to isolate actinomycete colonies having antibacterial activity from soil samples collected from different places around Rajshahi, Bangladesh. Thirty actinomycete colonies were isolated in pure culture from five soil samples using Starch-casein-nitrate-agar medium. The isolates were grouped in five color series based on their aerial mycelia color and screened for their antibacterial activity against a range of test bacteria. Sixteen isolates (53.3%) were found to have moderate to high activity against four gram-positive and four gram-negative bacteria. Since many isolates showed inhibitory activity against indicator bacteria, it is suggestive that Bangladeshi soil could be an interesting source to explore for antibacterial secondary metabolites.