Evaluation of Novel Design Strategies for Developing Zinc Finger Nucleases Tools for Treating Human Diseases

Table 1

List of exchanged amino acids in 2nd finger of SP1.

2nd finger	Amino acids in alpha helical region
SP1 (wild type)	R S D E L K R H K
	Exchanged Amino Acids
CB1	H S SR L I R H E
MR14	R S ST L IQ H K
MQ91	Q S SY L IK H K
MQ135	Q S SH L IQ H K
MQ151	Q S SY L TQ H K