Hsps Molecular weight (kDa) Cellular location Cellular functions References Hsp8.5 8 CyP Ubiquitination [57 , 58 ] Hsp10 10 M Stabilize catalytic subunit of DNA polymerase- [59 , 60 ] Hsp12 10–20 CyP, CW, PM Stress tolerance, maintaining cell morphology, cell adhesion, and germ tube formation [49 , 61 ] Hsp17 10–20 M Membrane lipid bilayer stabilizer [57 ] Hsp21 20–30 CW, ER Fungal adaptation in environmental stress and pathogenicity, glycerol and glycogen regulation, virulence factor in eukaryotic pathogens, and hyphal formation [62 , 63 ] Hsp26 20–30 CyP Induced in low pH conditions [28 , 64 ] Hsp27 20–30 N, CyP Cytoskeleton [57 ] Hsp30 30 PM Regulates membrane function under heat shock conditions, negatively regulates H+ ATPase
[40 ] Hsp31 30 ER Growth under partial pressure conditions and act as molecular chaperone [65 ] Hsp32 30 CyP Heme-oxygenase [57 , 63 ] Hsp40 40 CyS, M, ER Cell physiology and cofactor of Hsp70 [66 , 67 ] Hsp42 40 CyS Suppress the aggregation of nonnative protein [68 ] Hsp60 60 M, CyS Immunological properties, upregulated in biotic and abiotic stress [69 –71 ] Hsp70 68 CyS, N, ER, R, M Initial folding of nascent polypeptide and ATPase activity [34 , 72 , 73 ] Hsp78 70 M Mitochondrial thermotolerance and pressure tolerance [73 ] Hsp80 80 CyP Interact with unfolded polypeptide individually or in complex [73 ] Hsp82 80 CyP Pheromone signalling and negative regulation of Hsf1 [73 , 74 ] Hsp83 83 CyS Interaction with nascent chain polypeptide and signal transduction [24 ] Hsp88 88 CyS Interact with Hsp30 [75 , 76 ] Hsp90 90 CyS, ER, N Folding and maintenance of client proteins, involved in transcriptional and posttranscriptional processes and activation of signal transducers [72 , 77 ] Hsp100 100 CyS Catalytic activity and protease with ATPase activity [20 ] Hsp104 100 CyS Thermotolerance, survival at stationary phase, ethanol tolerance, reactivate denatured and aggregated proteins, and replication of yeast prions [29 , 78 , 79 ] Hsp105 105 N, CyP Not reported [57 , 80 ] Hsp110 110 N, CyP Misfolding of polypeptide and hydrolyses of ATP [57 , 81 , 82 ]
