The Use of Adenovirus Dodecahedron in the Delivery of an Enzymatic Activity in the Cell

Figure 2

The internalization of Pt-Dd in HeLa cell. (a) The HeLa cells were incubated for 1 h with Cy5 labeled Pt-Dd (in red) and the nuclei were counterstained by DAPI (in blue). (b) The HeLa cell expressing tubulin-GFP (in green) was incubated with Alexa 555 labeled Pt-Dd (in yellow) for 1 h. The pictures were taken on fluorescence microscopy (Olympus IX81®-UCB) equipped with 60x oil-immersion objective lens using the according filters or differential interference contrast (DIC).

(a)

(b)