Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency

Table 2

Relationship between risk factors and negative outcome.

Variables	Positive outcome (𝑛=67)	Negative outcome (𝑛=28)	Odds Ratio (95% CI)	𝑃
Age >75	41 (61%)	20 (71%)	1.59 (0.79–3.17)	.34
Male/Female	28/39 (42/58%)	15/13 (54/46%)	N/A	.57
IHD	47 (29%)	16 (31%)	0.57 (0.27–1.16)	.23
Cardiogenic shock	3 (5%)	4 (14%)	3.55 (0.74–16.93)	.07
Myocardial Infarction	4 (6%)	1 (4%)	0.59 (0.06–5.45)	.67
COPD	29 (44%)	10 (38%)	0.73 (0.31–1.69)	.49
Renal Failure	10 (32%)	2 (46%)	0.44 (0.09–2.13)	.31
p02< 60 at 2 hours	7 (17%)	3 (15% )	1.03 (0.25–4.26)	.96
Hemaglobin <10g/dL	5 (7%)	8 (29%)	4.10 (1.21–13.86)	.02
p02< 60 mmHg at presentation	34(38%)	17 (84.6)	1.50 (0.72–3.11)	.005
MAP <90 at presentation	9 (13%)	13(46%)	5.58 (2.01–15.52)	.001
Serum lactate >2.5 mmol/L at 2 hours	23 (37%)	25 (82%)	7.73 (2.60–22.90)	.0002
Lactate clearance <20% at 2 hours	9 (21%)	20 (69.2)	16.11 (6.53–39.70)	<.0001

IHD-ischemic heart disease; COPD–chronic obstructive pulmonary disease; CI-confidence interval.