Positive Fluid Balance Is Associated with Higher Mortality and Prolonged Mechanical Ventilation in Pediatric Patients with Acute Lung Injury

Table 1

Patient clinical characteristics and outcomes, (N = 313).

Clinical characteristic
Age, median (25–75% interquartile range)	3.4 yrs (1d–18 yrs)
Male,% (n)	56% (176)
PaO2/FiO2 at ALI onset^#	161 ± 74
Diagnoses associated with ALI, % (n)
Pneumonia	36% (112)
Aspiration	16% (50)
Sepsis	12% (39)
Near drowning	9% (28)
Cardiac*	7% (22)
Other	20% (62)
Nonpulmonary organ system failures at ALI onset	1.4 ± 1.5
PRISM III at ALI onset^#	10.3 ± 8.7
Exhaled TV (cc/kg IBW)^#	10.1 ± 4.3 cc/kg
Ventilator free days	14.8 ± 10.6 d
Mortality, % (n)	21% (67)

^#Mean ± standard deviation.
*Patients with any intracardiac shunts and/or left sided heart failure excluded.