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Critical Care Research and Practice
Volume 2011, Article ID 952956, 5 pages
http://dx.doi.org/10.1155/2011/952956
Research Article

Glasgow Coma Scale and Its Components on Admission: Are They Valuable Prognostic Tools in Acute Mixed Drug Poisoning?

1Poisoning Emeregncy Department, Noor and Ali Asghar Medical Center, Isfahan University of Medical Sciences, Ostandari Avenue, Isfahan 81458-31451, Iran
2Isfahan Clinical Toxicology Research Center, Noor and Ali Asghar Medical Center, Isfahan University of Medical Sciences, Ostandari Avenue, Isfahan 81458-31451, Iran
3Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran

Received 15 November 2010; Accepted 26 January 2011

Academic Editor: Larry M. Gentilello

Copyright © 2011 N. Eizadi Mood et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. The verbal, eye, and motor components of Glasgow coma scale (GCS) may be influenced by poisoned patients' behavior in an attempted suicide. So, the values of admission GCS and its components for outcomes prediction in mixed drugs poisoning were investigated. Materials and Methods. A followup study data was performed on patients with mixed drugs poisoning. Outcomes were recorded as without complications and with complications. Discrimination was evaluated by calculating the area under the receiver operating characteristic curves (AUC). Results. There was a significant difference between the mean value of each component of GCS as well as the total GCS between patients with and without complication. Discrimination was best for GCS (AUC: 0.933±0.020) and verbal (0.932±0.021), followed by motor (0.911±0.025), then eye (0.89±0.028). Conclusions. Admission GCS and its components seem to be valuable in outcome prediction of patients with mixed drug poisoning.