Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice

Figure 2

Bronchoalveolar lavage fluid thrombin-antithrombin complex (TATc) and plasminogen activator inhibitor (PAI)-1 levels in control mice (C) and mice ventilated for 5 hours with lower tidal volumes (L𝑉_𝑇) or higher 𝑉_𝑇 (H𝑉_𝑇). Each group consisted of heterozygote TF knockout mice (TF^+/−) and their wild-type littermates (TF^+/+). Data represent medians and interquartile range of six mice. *𝑃<0.05 versus TF^+/+ mice.

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