Critical Care Research and Practice / 2012 / Article / Tab 1

Research Article

Impact of Enzymatic Degradation of the Endothelial Glycocalyx on Vascular Permeability in an Awake Hamster Model

Table 1

Hemodymanical parameters and hematology.

Baseline60 minutes120 minutes
EnzymeControlEnzymeControlEnzymeControl

MAP114 (5)111 (6)109 (5)104 (9)106 (9)99 (5)*
HR459 (16)468 (17)455 (22)473 (18)454 (16)448 (16)*
Hct49 (2)50 (2)47 (2)47 (2)45 (2)**45 (2)***
Ph7.37 (0.03)7.35 (0.04)7.35 (0.04)7.32 (0.04)7.35 (0.02)7.32 (0.03)
PaO256.7 (9.9)54.4 (5.7)61.2 (5.9)59.5 (8.9)57.1 (10.9)59.2 (7.4)
PaCO256.6 (7.5)59.7 (3.89)56.1 (7.6)61.3 (6.6)55.7 (5.2)59.2 (2.7)
BE6.8 (2.8)6.9 (2.1)4.4 (1.6)4.7 (2.3)4.4 (1.6)3.9 (2.0)

Values are given as mean and standard deviation. MAP: mean arterial pressure, HR: heart rate, Hct: hematocrit, BE: base excess. Significant differences were seen within the groups from baseline to 120 minutes (MAP and Hct) and from 60 to 120 minutes in the control group (HR). * , ** , *** .

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