TY - JOUR
A2 - van Kaam, Anton
AU - Gonçalves, Américo
AU - Rocha, Gustavo
AU - Guimarães, Hercília
AU - Fernandes, Paula Cristina
AU - Proença, Elisa
AU - Oliveira, Dulce
AU - Rocha, Paula
AU - Quintas, Conceição
AU - Martins, Teresa
AU - Freitas, Alice
AU - Dias, Clara Paz
AU - Ramires, Albina
PY - 2012
DA - 2012/12/10
TI - Value of Chest Radiographic Pattern in RSV Disease of the Newborn: A Multicenter Retrospective Cohort Study
SP - 861867
VL - 2012
AB - Respiratory syncytial virus (RSV) lower respiratory tract infection is the most common viral respiratory infection in infants. Several authors have sought to determine which risk factors are the best predictors for severe RSV disease. Our aim was to evaluate if a specific chest radiographic pattern in RSV disease can predict the disease severity. We conducted a multicenter retrospective cohort study in term and preterm neonates with confirmed lower respiratory tract RSV infection, admitted to neonatal intensive care units (NICU) from 2000 to 2010. To determine which factors independently predicted the outcomes, multivariate logistic regression analysis was performed. A total of 259 term and preterm neonates were enrolled. Patients with a consolidation pattern on the chest radiograph at admission (n=101) had greater need for invasive mechanical ventilation (OR: 2.5; P=.015), respiratory support (OR: 2.3; P=.005), supplemental oxygen (OR: 3.0; P=.008), and prolonged stay in the NICU (>7 days) (OR: 1.8; P=.025). Newborns with a consolidation pattern on admission chest radiograph had a more severe disease course, with greater risk of invasive mechanical ventilation, respiratory support, supplemental oxygen, and prolonged hospitalization.
SN - 2090-1305
UR - https://doi.org/10.1155/2012/861867
DO - 10.1155/2012/861867
JF - Critical Care Research and Practice
PB - Hindawi Publishing Corporation
KW -
ER -