Table of Contents Author Guidelines Submit a Manuscript
Critical Care Research and Practice
Volume 2013, Article ID 760305, 7 pages
http://dx.doi.org/10.1155/2013/760305
Research Article

Retinol and Retinyl Palmitate in Foetal Lung Mice: Sexual Dimorphism

Histology and Embryology Institute, Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal

Received 8 August 2012; Revised 7 December 2012; Accepted 7 December 2012

Academic Editor: Manuel Sánchez Luna

Copyright © 2013 Olga Carvalho and Carlos Gonçalves. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. K. Biesalski and D. Nohr, “Importance of vitamin-A for lung function and development,” Molecular Aspects of Medicine, vol. 24, no. 6, pp. 431–440, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. F. Chytil, “The lungs and vitamin A,” American Journal of Physiology, vol. 262, no. 5, pp. L517–L527, 1992. View at Google Scholar · View at Scopus
  3. F. Chytil, “Retinoids in lung development,” The FASEB Journal, vol. 10, no. 9, pp. 986–992, 1996. View at Google Scholar · View at Scopus
  4. M. L. Pinto, P. Rodrigues, A. Honório, C. Gonçalves, and V. Bairos, “Vitamin A and lung development,” in Vitamin A: Nutrition, Side Effects and Supplements, L. P. Scott, Ed., pp. 1–46, Nova Science, 2010. View at Google Scholar
  5. C. Fraslon and J. R. Bourbon, “Retinoids control surfactant phospholipid biosynthesis in fetal rat lung,” American Journal of Physiology, vol. 266, no. 6, pp. L705–L712, 1994. View at Google Scholar · View at Scopus
  6. M. D. Metzler and J. M. Snyder, “Retinoic acid differentially regulates expression of surfactant-associated proteins in human fetal lung,” Endocrinology, vol. 133, no. 5, pp. 1990–1998, 1993. View at Publisher · View at Google Scholar · View at Scopus
  7. G. D. Massaro and D. Massaro, “Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats,” American Journal of Physiology, vol. 270, no. 2, pp. L305–L310, 1996. View at Google Scholar · View at Scopus
  8. G. D. Massaro and D. Massaro, “Retinoic acid treatment partially rescues failed septation in rats and in mice,” American Journal of Physiology, vol. 278, no. 5, pp. L955–L960, 2000. View at Google Scholar · View at Scopus
  9. G. D. C. Massaro, D. Massaro, W. Y. Chan et al., “Retinoic acid receptor-β: an endogenous inhibitor of the perinatal formation of pulmonary alveoli,” Physiological Genomics, vol. 4, no. 1, pp. 51–57, 2000. View at Google Scholar · View at Scopus
  10. R. H. Costa, V. V. Kalinichenko, and L. Lim, “Transcription factors in mouse lung development and function,” American Journal Respiratory Cell Molecular Biology, vol. 280, no. 5, pp. L823–L838, 2001. View at Google Scholar · View at Scopus
  11. C. Wongtrakool, S. Malpel, J. Gorenstein et al., “Down-regulation of retinoic acid receptor α signaling is required for sacculation and type I cell formation in the developing lung,” Journal of Biological Chemistry, vol. 278, no. 47, pp. 46911–46918, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Liu, C. S. Harvey, and S. E. McGowan, “Retinoic acid increases elastin in neonatal rat lung fibroblast cultures,” American Journal of Physiology, vol. 265, no. 5, pp. L430–L437, 1993. View at Google Scholar · View at Scopus
  13. G. D. Massaro and D. Massaro, “Formation of pulmonary alveoli and gas-exchange surface area: quantitation and regulation,” Annual Review of Physiology, vol. 58, pp. 73–92, 1996. View at Google Scholar · View at Scopus
  14. S. E. McGowan, C. S. Harvey, and S. K. Jackson, “Retinoids, retinoic acid receptors, and cytoplasmic retinoid binding proteins in perinatal rat lung fibroblasts,” American Journal of Physiology, vol. 269, no. 4, pp. L463–L472, 1995. View at Google Scholar · View at Scopus
  15. S. E. McGowan and J. S. Torday, “The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development,” Annual Review of Physiology, vol. 59, pp. 43–62, 1997. View at Publisher · View at Google Scholar · View at Scopus
  16. S. E. McGowan, M. M. Doro, and S. K. Jackson, “Endogenous retinoids increase perinatal elastin gene expression in rat lung fibroblasts and fetal explants,” American Journal of Physiology, vol. 273, no. 2, pp. L410–L416, 1997. View at Google Scholar · View at Scopus
  17. S. McGowan, S. K. Jackson, M. Jenkins-Moore, H. H. Dai, P. Chambon, and J. M. Snyder, “Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers,” American Journal of Respiratory Cell and Molecular Biology, vol. 23, no. 2, pp. 162–167, 2000. View at Google Scholar · View at Scopus
  18. W. Shi, F. Chen, and W. V. Cardoso, “Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease,” Proceedings of the American Thoracic Society, vol. 6, no. 7, pp. 558–563, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. J. S. Torday and V. K. Rehan, “Does “A” stand for alveolization?” European Respiratory Journal, vol. 23, no. 1, pp. 3–4, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Hind and M. Maden, “Retinoic acid induces alveolar regeneration in the adult mouse lung,” European Respiratory Journal, vol. 23, no. 1, pp. 20–27, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Maden, “Retinoids have differing efficacies on alveolar regeneration in a dexamethasone-treated mouse,” American Journal of Respiratory Cell and Molecular Biology, vol. 35, no. 2, pp. 260–267, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. J. P. Shenai, K. A. Kennedy, F. Chytil, and M. T. Stahlman, “Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia,” Journal of Pediatrics, vol. 111, no. 2, pp. 269–277, 1987. View at Google Scholar · View at Scopus
  23. J. P. Shenai, M. G. Rush, M. T. Stahlman, and F. Chytil, “Plasma retinol-binding protein response to vitamin A administration in infants susceptible to bronchopulmonary dysplasia,” Journal of Pediatrics, vol. 116, no. 4, pp. 607–614, 1990. View at Google Scholar · View at Scopus
  24. L. Rahmathullah, J. M. Tielsch, R. D. Thulasiraj et al., “Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India,” BMJ, vol. 327, no. 7409, pp. 254–257, 2003. View at Google Scholar · View at Scopus
  25. K. A. Kennedy, B. J. Stoll, R. A. Ehrenkranz et al., “Vitamin A to prevent bronchopulmonary dysplasia in very-low-birth-weight infants: has the dose been too low?” Early Human Development, vol. 49, no. 1, pp. 19–31, 1997. View at Publisher · View at Google Scholar · View at Scopus
  26. M. C. Bruce, C. E. Honaker, and R. J. Cross, “Lung fibroblasts undergo apoptosis following alveolarization,” American Journal of Respiratory Cell and Molecular Biology, vol. 20, no. 2, pp. 228–236, 1999. View at Google Scholar · View at Scopus
  27. M. Nakajoh, T. Fukushima, T. Suzuki et al., “Retinoic acid inhibits elastase-induced injury in human lung epithelial cell lines,” American Journal of Respiratory Cell and Molecular Biology, vol. 28, no. 3, pp. 296–304, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. S. K. Geevarghese and F. Chytil, “Depletion of retinyl esters in the lungs coincides with lung prenatal morphological maturation,” Biochemical and Biophysical Research Communications, vol. 200, no. 1, pp. 529–535, 1994. View at Publisher · View at Google Scholar · View at Scopus
  29. T. J. Desai, S. Malpel, G. R. Flentke, S. M. Smith, and W. V. Cardoso, “Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut,” Developmental Biology, vol. 273, no. 2, pp. 402–415, 2004. View at Publisher · View at Google Scholar · View at Scopus
  30. C. Mendelsohn, D. Lohnes, D. Décimo et al., “Function of the retinoic acid receptors (RARs) during development. (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants,” Development, vol. 120, no. 10, pp. 2749–2771, 1994. View at Google Scholar · View at Scopus
  31. Z. Wang, P. Dollé, W. V. Cardoso, and K. Niederreither, “Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives,” Developmental Biology, vol. 297, no. 2, pp. 433–445, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. P. Rodrigues, C. Gonçalves, and V. Bairos, “Metabolic pathways and modulating effects of vitamin A,” Current Medicinal Chemistry: Immunology, Endocrine and Metabolic Agents, vol. 4, no. 2, pp. 119–142, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. R. Blomhoff, M. H. Green, T. Berg, and K. R. Norum, “Transport and storage of vitamin A,” Science, vol. 250, no. 4979, pp. 399–404, 1990. View at Google Scholar · View at Scopus
  34. D. S. Goodman, “Vitamin A and retinoids in health and disease,” The New England Journal of Medicine, vol. 310, no. 16, pp. 1023–1031, 1984. View at Google Scholar · View at Scopus
  35. M. E. Newcomer and D. E. Ong, “Plasma retinol binding protein: structure and function of the prototypic lipocalin,” Biochimica et Biophysica Acta, vol. 1482, no. 1-2, pp. 57–64, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. N. Noy, “Retinoid-binding proteins: mediators of retinoid action,” Biochemical Journal, vol. 348, no. 3, pp. 481–495, 2000. View at Publisher · View at Google Scholar · View at Scopus
  37. J. L. Napoli, “Retinoic acid biosynthesis and metabolism,” The FASEB Journal, vol. 10, no. 9, pp. 993–1001, 1996. View at Google Scholar · View at Scopus
  38. T. Okabe, H. Yorifuji, E. Yamada, and F. Takaku, “Isolation and characterization of vitamin-A-storing lung cells,” Experimental Cell Research, vol. 154, no. 1, pp. 125–135, 1984. View at Google Scholar · View at Scopus
  39. J. P. Shenai and F. Chytil, “Vitamin A storage in lungs during perinatal development in the rat,” Biology of the Neonate, vol. 57, no. 2, pp. 126–132, 1990. View at Google Scholar · View at Scopus
  40. H. J. Maksvytis, C. Vaccaro, and J. S. Brody, “Isolation and characterization of the lipid-containing interstitial cell from the developing rat lung,” Laboratory Investigation, vol. 45, no. 3, pp. 248–259, 1981. View at Google Scholar · View at Scopus
  41. W. V. Cardoso, “Lung morphogenesis, role of growth factors and transcription factors,” in The Lung Development, Aging and the Environment, R. Harding, K. E. Pinkerton, and C. G. Plopper, Eds., cap. 1, pp. 3–11, Elsevier, London, UK, 2004. View at Google Scholar
  42. T. J. Desai, F. Chen, J. Lü et al., “Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis,” Developmental Biology, vol. 291, no. 1, pp. 12–24, 2006. View at Publisher · View at Google Scholar · View at Scopus
  43. S. Malpel, C. Mendelsohn, and W. V. Cardoso, “Regulation of retinoic acid signaling during lung morphogenesis,” Development, vol. 127, no. 14, pp. 3057–3067, 2000. View at Google Scholar · View at Scopus
  44. S. Bellusci, J. Grindley, H. Emoto, N. Itoh, and B. L. M. Hogan, “Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung,” Development, vol. 124, no. 23, pp. 4867–4878, 1997. View at Google Scholar · View at Scopus
  45. F. Chen, T. J. Desai, J. Qian, K. Niederreither, J. Lü, and W. V. Cardoso, “Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction,” Development, vol. 134, no. 16, pp. 2969–2979, 2007. View at Publisher · View at Google Scholar · View at Scopus