Table 2: Physiologic scores and laboratory values at the time of ICU admission.

No antiplatelets
N = 379
Antiplatelets
N = 272
P value

APACHE III 1 hour, median (IQR) 55 (42–68)57.5 (46–74.8)0.025
APS 1 hour, median (IQR) 35 (24–49)36 (25–49.8)0.64
Predicted hospital death %, median (IQR) 9.2 (4.9–17.4)10.4 (5.3–21.6)0.089
SOFA score day 1, median (IQR)7 (4–10)6 (4–9)0.054
ICU admission laboratory results
 Hemoglobin, g/dL, median (IQR)10.9 (9.4–12.5)11.1 (9.5–12.6)0.46
 Hematocrit %, median (IQR)32 (27.9–37)32 (28.3–36.9)0.45
 White blood cells, number * 1000/dL, median (IQR)12.3 (7.7–18.7)14.3 (9.4–19.5)0.017
 Platelets, number * 1000/dL, median (IQR)191 (122–285)212 (143–307)0.012
 Prothrombin time, sec, median (IQR)12.8 (10.9–18)11.9 (10.5–15)0.01
 International normalized ratio, median (IQR)1.3 (1.1–1.9)1.2 (1.1–1.6)0.01
 Bicarbonate, mmol/L, median (IQR)22 (19–25)22 (18–26)0.86
 Base excess, mmol/L, median (IQR) 4 (8–0)4 (8–0)0.76
 Lactate, mmol/L, median (IQR)2.3 (1.3–3.6)2 (1.3–3.5)0.56
 Baseline creatinine, mg/dL (IQR) 0.9 (0.7–1.1)1 (0.8–1.5)<0.001
  PaO2/FiO2 ratio, median (IQR)256 (157–382)278 (164–381)0.57

APACHE: Acute Physiologic and Chronic Health Evaluation, IQR: interquartile range, APS: Acute Physiology Score, SOFA: Sequential Organ Failure Assessment, %: percentage, g/dL: grams/deciliter, sec: seconds, mmol/L: millimol/liter, mg/dL: milligrams/deciliter, PaO2/FiO2: relation arterial partial pressure of oxygen/fraction of inspired oxygen.