Critical Care Research and Practice / 2014 / Article / Tab 3

Research Article

Acute Kidney Injury after Major Abdominal Surgery: A Retrospective Cohort Analysis

Table 3

Univariate and multivariate analysis to determine risk factors of postoperative acute kidney injury.

VariableUnadjusted OR
(95% CI)
Adjusted OR
(95% CI)

Preoperative characteristics
 Age (per year)1.05 (1.04–1.07)<0.00011.02 (1.01–1.05)0.049
 Male1.5 (0.9–2.4)0.07
 Caucasian 0.8 (0.3–2.3)0.680
 Solid malignancy1.9 (1.2–2.9)0.0051.4 (0.8–2.4)0.274
 ASA physical status IV/V2.5 (1.2–4.9)0.011.1 (0.4–2.5)0.931
 Nonrenal RCRI (per point)2.9 (1.9–4.3)<0.00011.9 (1.3–3.1)0.003
 Preoperative hemoglobin (per g/dL)0.8 (0.7–0.9)<0.00011 (0.8–1.2)0.825
 Preoperative SCr (per mg/dL increase)2.3 (1.5–3.4)<0.00011.2 (0.7–2)0.411
 Urgency surgery1.3 (0.8–2.1)0.368
Type of surgery
 Laparoscopy versus laparotomy0.6 (0.3–1.2)0.139
 Colorectal1.9 (1.2–2.9)0.0061.6 (0.9–2.7)0.122
 Gastric0.6 (0.3–1.1)0.630
 Hepatobiliary and pancreatic10.6 (0.3–1.2)0.144
 Small bowel1.2 (0.4–3.5)0.680
 Esophageal1.3 (0.3–5)0.698
 Other surgery0.6 (0.2–1.3)0.559
Intraoperative characteristics
 Duration of anesthesia (per 10 min.)1.02 (1–1.05)0.0241.01 (0.9–1.1)0.208
 IOH (per record)1.2 (1.1–1.4)0.0011.1 (0.9–1.2)0.437
 Crystalloids with colloids versus crystalloids without colloids 3 (1.8–5)<0.00011.6 (0.9–3)0.143
 Erythrocytes (per unit)3.7 (2.4–5.8)<0.00012.2 (1.4–3.5)<0.0001
 Vasoactive drugs use1.8 (1.1–3)0.0391.1 (0.5–2)0.939
 Nonrenal SAPS II (per point)1.07 (1.05–1.09)<0.00011.03 (1.01–1.06)0.019

OR: odds ratio. CI: confidence interval. COPD: ASA: American Society of Anesthesiologists. RCRI: Revised Cardiac Risk Index. SCr: serum creatinine. IOH: intraoperative hypotension. SAPS II: Simplified Acute Physiology Score, version II. 1Hepatobiliary and pancreatic surgery includes gallbladder surgery ( ), hepatic surgery ( ), pancreatic surgery ( ), and bile ducts surgery ( ).