The Impact of Intravenous Lidocaine on ICP in Neurological Illness: A Systematic Review

Table 3

Oxford and GRADE level of evidence.

Reference	Study type	Oxford level of evidence	GRADE level of evidence
Bedford et al. [6]	Prospective nonrandomized	2b	B
Bedford et al. [7]	Prospective randomized trial	2b	B
Donegan and Bedford [8]	Prospective cohort	2b	C
Donegan et al. [9]	Prospective cohort	2b	C
Grover et al. [10]	Prospective randomized trial	2b	B
Hamill et al. [11]	Prospective randomized trial	2b	B
Hirayama et al. [12]	Prospective nonrandomized	2b	C
Montarry et al. [13]	Prospective cohort	2b	C
Samaha et al. [14]	Prospective randomized trial	2b	B
White et al. [15]	Prospective cohort	2b	C
Yano et al. [16]	Prospective cohort	2b	C

Donegan and Bedford [8] and Donegan et al. [9] are companion publications, with Donegan et al. [9] representing the meeting abstract published prior to the full manuscript [8]. The data from Donegan et al. [9] is not included in the synthesis of data and is only included in the tables for completeness.