Clinical Study

Additional Analgesia for Central Venous Catheter Insertion: A Placebo Controlled Randomized Trial of Dexmedetomidine and Fentanyl

Table 1

Patients characteristics and baseline variables.

VariableDexmedetomidine ()Fentanyl ()Placebo () value

Age in years39.4 ± 13.538.4 ± 11.440 ± 9.70.898
M/F ()13/712/79/110.370
Weight (kg)56 ± 11.956 ± 12.559 ± 12.30.703
ASA PS 1/2 ()12/813/614/60.774
Heart rate81 ± 8.580.5 ± 7.282 ± 8.50.830
SBP (mmHg)126.4 ± 14.9125 ± 11.2125.5 ± 13.80.967
SpO2 (%)99.6 ± 0.599.7 ± 0.499.6 ± 0.60.738
Respiratory rate17.7 ± 1.817.4 ± 1.817.2 ± 2.00.664
Number of attempts1.1 ± 0.361.2 ± 0.451.2 ± 0.410.692
Procedural time (in seconds)1423 ± 2061261 ± 2321304 ± 2750.100

Values are mean ± standard deviation or numbers ().
American Society of Anesthesiologists physical status 1/2.
SBP: systolic blood pressure.
An attempt is defined as the introducer needle’s entry into the skin and its removal from the skin.
Time from skin puncture to anchoring the last suture to the skin for central venous catheter fixation.