Research Article

Outcome in Patients with Isolated Moderate to Severe Traumatic Brain Injury

Table 1

Baseline characteristics and mortality.

VariableAll patients ()WLST ()Non-WLST () value

Mortality, (%)55 (33)100 (45)0
Median age in years (IQR)57 (32.5)67 (22)54 (35.25)
 Mean rank agen/a114.5674.27<0.001
Median ISS (IQR)20 (9)25 (9)20 (9)0.01
Median AIShead (IQR)4 (1)5 (1)4 (1)
 Mean rank AISheadn/a108.4776.48<0.001
Female, (%)62 (37)16 (36)46 (37)0.854
Trauma mechanism, (%)0.061
 Fall stairs or height53 (32)19 (44)34 (28)
 Fall low height/collaps or nos15 (24)8 (19)16 (13)
 Traffic accident: two wheels60 (36)11 (26)49 (41)
 Traffic accident: car12 (7)1 (2)11 (10)
 Traffic accident: pedestrian4 (2)1 (2)3 (3)
 Hit by subject6 (4)0 (0)6 (5)
 Penetrating injury3 (2)2 (5)1 (1)
 Hanging2 (1)1 (2)1 (1)
 Missing5(3)2 (4)3 (2)
Charlson Comorbidity Index (IQR)
 Median0 (1)0 (1)
 Mean rank88.3781.230.302
Anticoagulant users, (%)
 None or platelet aggregation inhibitors32 (82)116 (94)0.043
 Coumarins/heparines/NOAC7 (18)7 (6)
 Missing6 (13)1 (1)
GCS in ED (IQR)
 Median7 (8)8.5 (5)
 Mean rank47.5464.510.030
 Sedated, (%)20 (44)28 (23)
Motor score in ED (IQR)
 Median5 (4)5 (1)0.009
 Missing, (%)20 (44)28 (23)
Pupil reflexes in ED, (%)
 None or one eye21 (50)17 (15)<0.001
 Both eyes21 (50)96 (85)
 Missing3 (7)11 (9)
Corneal reflexes in ED, (%)
 None or one eye11 (58)4 (17)0.009
 Both eyes8 (42)20 (83)
 Missing26 (58)100 (81)
Sedation, (%)20 (44)28 (23)0.005
Signs on first CT scan, (%)
 Epidural hemorrhage17 (38)42 (34)0.716
 Subdural hemorrhage43 (96)93 (75)0.004
 Subarachnoidal hemorrhage39 (87)91 (74)0.097
 Compression basal cisterns34 (76)52 (42)<0.001
 Midline shift25 (56)33 (27)0.001

WLST: withdrawal of life-sustaining treatment; AIShead: Abbreviated Injury Score of the head region. 10 patients who died due to other causes than WLST are included in this analysis.