Prevalence and Temporal Distribution of Extrasystoles in Septic ICU Patients: The Feasibility of Predicting Fluid Responsiveness Using Extrasystoles

Table 1

Demographics and clinical characteristics of the cohorts.

	Selected cohort (n = 50)	Matched subset with sepsis omitting selected cohort (n = 429)	Entire matched subset omitting selected cohort (n = 2461)
Age	68 (54; 76)	69 (52; 78)	68 (55; 79)
Male gender	25 (50%)	228 (53%)	1410 (57%)
ICU admission type
(i) CCU	11 (22%)	146 (34%)	878 (36%)
(ii) CSRU	15 (30%)	126 (29%)	715 (29%)
(iii) MICU	24 (48%)	157 (37%)	854 (35%)
(iv) SICU	0 (0%)	0 (0%)	13 (1%)
(iv) NICU	0 (0%)	0 (0%)	1 (0%)
First SOFA score	10 (7; 13)	6 (3; 9)#	5 (2; 9)#
Elixhauser sum score	3 (2; 4)	2 (1; 4)	2 (1; 3)∗
Comorbidity related to ES
(i) Heart disease	28 (56%)	200 (47%)	1019 (41%)∗
(ii) Hypertension	9 (18%)	108 (25%)	655 (27%)
Primary diagnosis
Sepsis	15	NA	NA
Pulmonary	13	NA	NA
Cardiac function/arrhythmia	6	NA	NA
AMI	3	NA	NA
Hepatic	2	NA	NA
CNS	2	NA	NA
GI bleeding	1	NA	NA
Renal	3	NA	NA
Vasopressor use	21 (42%)	NA	NA
MAP (24 h mean)	75.7 (68.5; 84.8)	NA	NA
HR (24 h mean)	87.8 (74.9; 98.5)	NA	NA

Statistical comparisons are made between the selected cohort and the matched subset with sepsis (n = 429) and between the selected cohort and the remaining matched subset (n = 2461). Data are presented as median (interquartile range) for continuous and ordinal variables and as number (fraction of entire cohort in percent) for dichotomous variables. Primary diagnoses are reported with respect to the affected organ system, except for the sepsis diagnose. compared with selected cohort. ^# compared with selected cohort. CCU: Coronary Care Unit; CSRU: Cardiac Surgery Recovery Unit; MICU: Medical ICU; SICU: Surgical ICU; NICU: Neonatal ICU; GI: gastrointestinal; ES: extrasystoles; AMI: acute myocardial infarction; CNS: central nervous system; GI: gastrointestinal; MAP: Mean arterial pressure; HR: Heart rate; NA: not assigned.