Critical Care Research and Practice / 2019 / Article / Tab 4

Review Article

Renal Replacement Therapy in the Critical Care Setting

Table 4

Comparison of various RRT modalities.


Duration4 hrs daily
/alternate days
6–12 hrs daily
/alternate days
24 hrs (though achieves 16 hrs on avg.)
Haemodynamic instabilityLeast suitableGoodMost compatible
Compatible with extracorporeal life supportNoNoYes
In raised intracranial pressureIncreasesCan increaseUsually no change
Anti-coagulationCan be omittedCan be omittedPredilution can be utilised to maintain circuit
Serum concentration of renally cleared drugsMajor fluctuationsSome fluctuationLeast fluctuation
Vascular accessAV fistula or nontunnelled or tunnelled catheterAV fistula or nontunnelled or tunnelled catheterNontunnelled or tunnelled catheter
Compatible with supporting large volume infusions (antibiotics, nutrition, etc.)NoWould need to be daily and longer sessionsMost compatible
MobilisationMost compatibleCould be compatible if done at night/rest timeNot compatible—would need to be discontinued.

IHD : intermittent haemodialysis; SLED : sustained low-efficiency dialysis; CRRT : continuous renal replacement therapy.