Contribution of Levosimendan in Weaning from Mechanical Ventilation in Patients with Left Ventricular Dysfunction: A Pilot Study

Table 3

Absolute change in echocardiographic parameters on spontaneous breathing trial (SBT) before and after levosimendan infusion ().

		value
Delta LVEF (%)	4.6 ± 4.9	0.01
Delta E velocity (cm/s)	−2.0 ± 1.9	0.65
Delta A velocity (cm/s)	9.0 ± 2.2	0.27
Delta deceleration time (ms)	21.4 ± 34.4	0.08
Delta e′ velocity (cm/s)	2 ± 2	0.02
Delta E/e′ ratio	−2.90 ± 3.34	0.01
Delta E/A ratio	−0.27 ± 0.59	0.24

Differences were calculated as 2nd – 1st SBT values. E, peak velocity of E-wave; A, peak velocity of A-wave measured using Doppler transmitral flow; e′ early mitral annulus diastolic velocity measured using tissue Doppler imaging; LVEF, left ventricular ejection fraction.