Research Article

Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial

Table 2

Epidemiologic and environmental characteristics of the studied cohort.

ParametersGroup AGroup BTotalP
MelatoninPlacebo
N = 21N = 12N = 33
Median (IQR)Median (IQR)Median (IQR)

Age (years)55 (43–66)57.5 (50–64)55 (49–66)0.50
APACHE II22 (12–30)24 (14–28)22 (14–29)0.81
APACHE III74 (53–94)78 (47–101)74 (53–94)0.90
ICU length of stay (days)24 (16–36)23 (16–35)23 (16–36)0.71
Study ICU enrollment day8 (6–15)10 (3–14)10 (3–14)0.62
Light intensity (lux)N = 1450 (25–60)50 (30–65)50 (25–63)0.69
Sound intensity (dB)N = 1460 (50–62)65 (65–70)62 (50–65)0.12

lux, luxes; dB, decibels.