Research Article

Lactate Arterial-Central Venous Gradient among COVID-19 Patients in ICU: A Potential Tool in the Clinical Practice

Table 1

Baseline characteristics on ICU admission and ICU outcomes of the enrolled population.

VariableMedian (IQR)

Age (years)66.0 (55.0–71.0)
Charlson comorbidity index2.0 (1.0–3.0)
SAPS II score37.0 (29.0–41.5)
Brixia score10.0 (9.0–11.5)
Interleukin-6 (pg/mL)40.3 (10.0–759.5)
Alanine aminotransferase (U/L)32.0 (20.5–83.5)
Creatinine (mg/dL)0.75 (0.58–0.87)
PaO2/FiO2 ratio195.0 (152.5–219.5)
PaCO2 (mmHg)51.7 (41.6–55.6)
Arterial lactate (mmol/L)1.65 (0.96–2.07)
Central venous lactate (mmol/L)1.44 (0.76–1.84)
Delta a-cv lactate (mmol/L)0.15 (0.07–0.25)
Length of mechanical ventilation (days)19.0 (10.0–42.0)
Length of stay in ICU (days)22.0 (12.50–49.50)
Survival rate at ICU discharge (n; %)16; 76.2%

ICU: intensive care unit; IQR: interquartile range; SAPS II: Simplified Acute Physiology Score; a-cv: arterial-central venous.