Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

Table 2

ICU patient variables.

	Nonsurvivors (n = 28)	Survivors (n = 28)	values
Median hours of mechanical ventilation (h)	442 (188–800)	523 (327–765)	0.4891
SAPS II (mean ± SD)	44.8 ± 10.7	44.9 ± 16.0	0.7727
APACHE II (mean ± SD)	25.3 ± 7.7	26.8 ± 13.4	0.9529
SOFA	11.9 ± 2.8	10.7 ± 2.7	0.1262
Renal replacement therapy in ICU	17 (60.7%)	15 (53.6%)	0.7875
Median days length of ICU stay (interquartile range)	18.5 (9–36.75)	24 (15.5–32.00)	0.2515
Median days duration of ECMO (interquartile range)	16 (7–28.75)	18 (8.5–24.0)	0.9838
Variables before ECMO implantation
Median days of invasive ventilation (interquartile range)	1.0 (1–5)	1 (0–3)	0.2701
Median pO2/FiO2 ratio (interquartile range) (mmHg)	62 (48–89)	67 (61–90)	0.2223
Median pCO2 (interquartile range) (mmHg)	51 (47–60)	51 (47–57)	0.5896
Fluid balance 24 hours after ICU admission
Median fluid balance (interquartile range) (ml)	2125 (0–4017)	1375 (131–3334)	0.9795
Hemodynamic, respiratory, and biochemical variables
Median norepinephrine (interquartile range) (µg/kg/min)
Before ECMO	0.14 (0.00–0.33)	0.1 (0–0.33)	0.8553
12 h after ECMO	0.08 (0.00–0.24)	0.09 (0.02–0.20)	0.8827
Median serum lactate (interquartile range) (mmol/l)
Before ECMO	2.0 (1.2–3.6)	1.4 (0.9–3.0)	0.2758
12 h after ECMO	1.9 (1.2–3.4)	1.5 (1.0–2.6)	0.2127
Heart rate (beats/minute)
Before ECMO	106 ± 21	98 ± 20	0.3419
12 h after ECMO	91 ± 21	88 ± 18	0.7402
Mean arterial pressure (mmHg)
Before ECMO	78 ± 13	80 ± 15	0.4051
12 h after ECMO	74 ± 11	72 ± 9	0.3815