Research Article

Validation of the Acute Physiology and Chronic Health Evaluation (APACHE) II and IV Score in COVID-19 Patients

Table 3

Results of the univariate logistic regression model.

Severity score valueOR (95% CI)AUCHL statistic ( value)

Total group
 APACHE II0.03511.10 (1.01, 1.21)0.6310.98 (0.1394)
 APACHE IV0.00421.05 (1.02, 1.08)0.672.54 (0.9234)
 SOFA on admission0.15011.11 (0.96, 1.27)0.5310.06 (0.0736)
 Comparison of AUC ROC
  APACHE IV versus APACHE II0.4835
  APACHE IV versus SOFA0.0389
  APACHE II versus SOFA0.1181

Current treatment group
 APACHE II0.02601.17 (1.02, 1.34)0.705.10 (0.6475)
 APACHE IV0.00181.11 (1.04, 1.18)0.823.06 (0.8017)
 SOFA on admission0.14641.20 (0.94, 1.52)0.499.97 (0.0760)
 Comparison of AUC ROC
  APACHE IV versus APACHE II0.1477
  APACHE IV versus SOFA0.0047
  APACHE II versus SOFA0.1271

The statistical significance of the severity score, the odds ratio (OR) and 95% confidence interval, the AUC values, and the Hosmer–Lemeshow (HL) test statistics are displayed for the overall group and current treatment group.