Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism

Table 3

Age- and sex-adjusted main effects of breastfeeding and ESR1 predicting depression.

	BDI-II dichotomous depression		BDI-II continuous depression		BDI modified depression
	OR (95% CI)	𝑃	Mean (std. error)	𝑃	Mean (std. error)	𝑃
Breastfeeding		.054		.047		.151
Yes	1.00		5.14 (0.19)		2.05 (0.02)
No	1.82 (0.99–3.36)		6.55 (0.68)		2.16 (0.07)
ESR1 genotype		.872		.766		.486
T/T	1.00		5.33 (0.31)		2.09 (0.03)
T/C	0.93 (0.62–1.40)		5.11 (0.26)		2.04 (0.03)
C/C	0.86 (0.48–1.54)		5.45 (0.46)		2.04 (0.05)