The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Table 6

Comparison of NF-κB mRNA expression levels between groups.

Comparison Groups	P Value
Control x Low Dose Pitavastatin	0.001
Control x High Dose Pitavastatin	0.002
Control x TNF-α	0.001
Control x Low Dose Pitavastatin + TNF-α	0.001
Control x High Dose Pitavastatin + TNF-α	0.001
Control x DMSO	1.000
Low Dose Pitavastatin x High Dose Pitavastatin	0.002
Low Dose Pitavastatin x TNF-α	0.001
Low Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.001
Low Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.001
Low Dose Pitavastatin x DMSO	0.001
High Dose Pitavastatin x TNF-α	0.002
High Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.002
High Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.002
High Dose Pitavastatin x DMSO	0.002
Low Dose Pitavastatin + TNF-αx TNF-α	0.205
Low Dose Pitavastatin + TNF-αx High Dose Pitavastatin + TNF-α	0.673
Low Dose Pitavastatin + TNF-αx DMSO	0.001
High Dose Pitavastatin + TNF-αx TNF-α	0.205
High Dose Pitavastatin + TNF-αx DMSO	0.001
TNF-α x DMSO	0.001

NF-κB, nuclear factor-kappa B; TNF-α, tumor necrosis factor-α; DMSO, dimethyl sulfoxide.