Stroke Risk Status, Anticoagulation Treatment, and Quality-of-Life in Chinese Patients with Atrial Fibrillation: China Registry of Atrial Fibrillation (CRAF)

Table 2

Risk factors for underuse of anticoagulants in patients with moderate-to-high risk NVAF and patients with VAF.

Risk factors	NVAF			VAF
	OR	95% CI	p-Value	OR	95% CI	p-Value
Age (per 10 years)	1.122	(1.040, 1.210)	0.003	1.517	(1.277, 1.802)	<0.001
SBP (per 10 mmHg)	1.102	(1.051, 1.155)	<0.001	0.855	(0.744, 0.982)	0.026
DBP (per 10 mmHg)				1.356	(1.106, 1.662)	0.003
Regions (vs middle)
Northeast	1.900	1.164, 3.101	0.010
East	1.438	1.176, 1.760	<0.001
West	1.270	0.969, 1.665	0.083
Hospital level (vs tertiary)	0.420	0.324, 0.543	<0.001	0.539	(0.335, 0.865)	0.010
Type of AF (vs persistent/permanent)
New-onset	1.857	1.412, 2.441	<0.001	1.978	(0.975, 4.013)	0.059
Paroxysmal	1.768	1.470, 2.128	<0.001	1.761	(1.072, 2.895)	0.026
Dyslipidemia	0.718	0.591, 0.873	0.001
History of CAD				0.198	(0.061, 0.644)	0.007
History of thromboembolism	0.640	0.520, 0.789	<0.001
Antiarrhythmic treatment	0.359	0.271, 0.475	<0.001	0.461	(0.258, 0.823)	0.009

AF: atrial fibrillation; CAD: coronary artery disease; CI: confidence interval; DBP: diastolic blood pressure; NVAF: non-valvular atrial fibrillation; OR: odds ratio; SBP: systolic blood pressure; VAF: valvular atrial fibrillation.