Identification of Differentially Expressed Genes and Signaling Pathways in Acute Myocardial Infarction Based on Integrated Bioinformatics Analysis
Volcano plot of gene expression profile data in AMI samples and sham-operation ones and correlation coefficient analysis diagram. Notes: (a) volcano plot of GSE775, (b) volcano plot of GSE19322, and (c) volcano plot of GSE97494. The red, green, and gray points represent upregulated genes, downregulated genes, and nondifferentially expressed genes, respectively. They are screened on the basis of log2FC >1.0 and a corrected p <0.05. (d) Correlation coefficient analysis diagram. Each column and row, respectively, represents one sample. Red represents strong correlation between samples and grey represents weak correlation between samples. Different shades of colors indicate the different correlation degree. Abbreviation: AMI, acute myocardial infarction; DEGs, differentially expressed genes; FC, fold change.