New Insights into the Association between Fibrinogen and Coronary Atherosclerotic Plaque Vulnerability: An Intravascular Optical Coherence Tomography Study

Table 5

Coronary angiographic findings and OCT analysis in patients according to serum fibrinogen levels.

	Group	Fibrinogen<4.0	Fibrinogen>4.0	t/x^2	P
FCT(μm)		140 (60,230)	110 (30,200)	1.055	0.291
Lipid arc, degree		116 (0,174)	107 (0,178)	0.008	0.994
Rupture (%)	No	117 (90.0)	20 (83.3)	0.364	0.546
	Yes	13 (10.0)	4 (16.7)
ACS-IFC (%)	No	116 (89.2)	18 (75.0)	2.481	0.115
	Yes	14 (10.8)	6 (25.0)
Macrophage accumulation	0	71 (54.6)	14 (58.3)	4.744	0.303
	1	36(27.7)	3 (12.5)
	2	20 (15.4)	7 (29.2)
	3	2 (1.5)	0 (0.0)
	4	1 (0.8)	0 (0.0)
Vasa vasorum	No	117 (90.0)	22 (91.7)	0.000	1.000
	Yes	13 (10.0)	2 (8.3)
Thrombus	No	104 (80.0)	17 (70.8)	1.011	0.315
	Yes	26 (20.0)	7 (29.2)
Diameter stenosis, %		74.43±17.17	72.29±14.74	0.572	0.568
Calcified nodule	No	123 (94.6)	22 (91.7)	0.009	0.926
	Yes	7 (5.4)	2 (8.3)
TCFA		25 (19.2)	5 (20.8)	0.000	1.000
Minimal lumen area (mm^2)		3.57±2.03	2.92±1.46	1.511	0.133
Normal lumen area (mm^2)		10.60±3.13	9.90±3.30	1.000	0.319
Lesion Length		9.74±3.61	8.64±2.90	1.413	0.160
Characteristic of plaque	Lipid	84 (64.6)	15 (62.5)	0.042	0.979
	Calcified	20 (15.4)	4 (16.7)
	Fibrotic	26 (20.0)	5 (20.8)
Target vessel	LAD, n (%)	98 (75.4)	17 (70.8)	3.436	0.179
	LCX, n (%)	7 (5.4)	4 (16.7)
	RCA, n (%)	25 (19.2)	3 (12.5)
Location of target plaque	Proximal	89 (68.5)	12 (50.0)	3.590	0.155
	Mid	39 (30.0)	12 (50.0)
	Distal	2 (1.5)	0 (0.0)

Abbreviations are the same as in Table 2.