(i) Cardiac function preserved in 92% of patients (ii) Mean duration on inotropic support – 113 ± 85 hours (iii) Length of ICU stay – 6 days (iv) Longest period of OCS support - 464 minutes
(i) Survival rate of 95% at 30 days and 6 months and 87% at one year and four years, respectively. (ii) No post-transplant vasculopathy incidences were reported
(i) 4 hearts were able to resuscitated (ii) 3 were transplantable with excellent visual contractility and lactate trends (iii) One was found unsuitable for transplantation with abnormal lactate levels and impaired contractility
OCS Hearts (i) All OCS hearts are able to be weaned off cardiopulmonary bypass (CBG) and support the animal’s circulation with the use of inotropic support (ii) Stable hemodynamics 3 hours post weaning Cold Storage (CS) (i) None of the 3 hearts in the CS group could be weaned from CPB, despite escalation of inotrope doses. (ii) Unable to establish stable cardiac rhythm (iii) Poor contractility
(i) Cold Storage: Cold & Total Ischemic Time (195 min) 30-day survival rate (97%) (ii) No significant difference in MACE, rejection rates and length of ICU stay in OCS and CS group respectively (13 vs 14%; 18 vs 14%; 147 days vs 137 days)
(i) Cold storage: Cold & total ischemic time - 207 ± 50 min (ii) No difference in 2-year patient survival rate (OCS: 72.2%; cold storage: 81.6%; p = 0.38) (iii) Allograft rejection (OCS: 53%; cold storage: 61.8%) (iv) No difference in MACE and vasculopathy incidences