Research Article
MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy
Table 3
KEGG pathway analysis of DEGs.
| | Pathway | ID | Count | value | Genes |
| | ECM-receptor interaction | hsa04512 | 5 | 4.03-09 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B | | Dilated cardiomyopathy (DCM) | hsa05414 | 5 | 6.84-09 | ITGA1|ITGB3|PRKACA|ITGB1|ITGA2B | | Human papillomavirus infection | hsa05165 | 6 | 8.06-08 | THBS2|ITGB1|ITGB3|PRKACA|ITGA1|ITGA2B | | Focal adhesion | hsa04510 | 5 | 2.31-07 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B | | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | hsa05412 | 4 | 2.55-07 | ITGA1|ITGB3|ITGB1|ITGA2B | | Hypertrophic cardiomyopathy (HCM) | hsa05410 | 4 | 4.65-07 | ITGA1|ITGB3|ITGB1|ITGA2B | | Platelet activation | hsa04611 | 4 | 1.60-06 | ITGB3|PRKACA|ITGB1|ITGA2B | | Phagosome | hsa04145 | 4 | 3.52-06 | ITGB3|THBS2|ITGB1|C3 | | PI3K-Akt signaling pathway | hsa04151 | 5 | 3.71-06 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B | | Proteoglycans in cancer | hsa05205 | 4 | 1.08-05 | ITGB3|PRKACA|ITGB1|PTPN6 | | Regulation of actin cytoskeleton | hsa04810 | 4 | 1.32-05 | ITGA1|ITGB3|ITGB1|ITGA2B | | Leishmaniasis | hsa05140 | 3 | 1.89-05 | ITGB1|PTPN6|C3 | | Complement and coagulation cascades | hsa04610 | 3 | 2.29-05 | PLAT|A2M |C3 | | Hematopoietic cell lineage | hsa04640 | 3 | 4.15-05 | ITGA1|ITGB3|ITGA2B | | Fluid shear stress and atherosclerosis | hsa05418 | 3 | 0.000117572 | ITGB3|PLAT|ITGA2B | | Cholesterol metabolism | hsa04979 | 2 | 0.00056172 | APOE|APOB | | Thyroid hormone synthesis | hsa04918 | 2 | 0.001195438 | PRKACA|ALB | | Pertussis | hsa05133 | 2 | 0.001258577 | ITGB1|C3 | | Rap1 signaling pathway | hsa04015 | 3 | 0.00038722786 | ITGB3|ITGB1|ITGA2B | | ECM-receptor interaction | hsa04512 | 5 | 4.03-09 | ITGA1|ITGB3|THBS2|ITGB1|ITGA2B |
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Abbreviation: KEGG: Kyoto Encyclopedia of Genes and Genomes; DEGs: differentially expressed genes.
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