Cardiovascular Therapeutics

Research Article

Analysis of Clinical Efficacy of Traditional Chinese Medicine in Recovery Stage of Stroke: A Systematic Review and Meta-Analysis

Table 2

Intervention characteristics of included studies.


	Study ID (name, year)	Treatment group	Control group	Duration/follow-up	Outcome measures

TCMs	Wang Yuxiu, 2017	TCM-1 (3 tablets, tid)+RT	RT	8 weeks/NR	TC, TG, LDL, HDL, hs-CRP, HCY
	Zhao Xiaoli, 2017	TCM-3, bid+TCM-4, bid+RT	RT	2 months/NR	TC, HDL, LDL, TG, HCT
	Chen Si, 2016	TCM-5, tid+RT	RT	14 days/NR	hs-CRP, FIB
	Li Shefang, 2016	TCM-6, ivdrip, qd+RT	RT	1 month/NR	TER, NIHSS
	Zhang Kefei, 2018	TCM-7, po+RT	RT	4 weeks/NR	TG, TC, NIHSS, Bl, WHV, WLV, PV
	Zhao Jing, 2016	TCM-1 (3 tablets, tid)+RT	RT	12 months/NR	TC, TG, HDL, LDL, NIHSS
	Yang Zhenwei, 2017	TCM-8, po, qd+RT	RT	3 months/NR	NIHSS, HCY
	Liu Yupeng, 2016	TCM-2+RT	RT	4 weeks/NR	FMA, Bl
	Cao Ying, 2014	TCM-9, 4 tablets, tid+RT	RT	28 days/NR	TER
	Fu Yaping, 2018	TCM-10, 200 ml/d, bid+RT	RT	8 weeks/NR	TER, SITCM, NIHSS
	Li Yaorong, 2015	TCM-11, ivdrip, qd+RT	RT	14 days/NR	TER, HCT, FIB
	Wu Xiuhua, 2018	TCM-12, 3 tablets, tid+RT	RT	3 months/NR	TER, NIHSS, FIB
	Chen Rong, 2011	TCM-13, bid+RT	RT	14 days/NR	NIHSS, Bl
	Zhong Lingyi, 2019	TCM-2, bid+RT	RT	8 weeks/NR	TER, hs-CRP
	Jia Liang, 2017	TCM-14, bid+RT	RT	8 weeks/NR	FMA, Bl, HCY
	Zhang Jin, 2004	TCM-15, bid+RT	RT	28 days/NR	TER, FIB, TC, TG, LDL, HDL
	Wang Chengtai, 2016	TCM-16, bid+RT	RT	4 weeks/NR	TER, hs-CRP, FIB, HCY
	Niu Ben, 2016	TCM-17, bid+RT	RT	8 weeks/NR	TER, BI, HCY
	Wang Aili, 2019	TCM-2, bid+RT	RT	6 weeks/NR	NIHSS, SITCM, FIB, TER
	Yuan Li, 2005	TCM-18, 0.4 g/time, ivdrip+RT	RT	28 days/NR	TER, FIB, TC, TG, HDL, LDL
	Liu Weicheng, 2017	TCM-19, tid, 2 bags/time+RT	RT	1 month/NR	TER, TC, TG, FIB, WHV, WLV, PV
	Li Naiqian, 2017	TCM-20, 200 ml/d, bid+RT	RT	15 days/12 months	NIHSS, Bl, HCY, hs-CRP, FIB
	Bian Yonghong, 2017	TCM-21, 200 ml/d, bid+RT	RT	8 weeks/NR	NIHSS, HCT
	Lou Fei, 2019	TCM-22, 3 tablets, tid+RT	RT	12 weeks/NR	NIHSS, HCY, SITCM

ACU	Cai Jingjing, 2012	Acupuncture+RT1	RT1	4 weeks/NR	ADL
	Chen Dan, 2018	Acupuncture+RT	RT	4 weeks/NR	SSA, VFSS
	Dai Shuqing, 2015	Acupuncture, qd+RT2	RT2	36 days/NR	FMA, NIHSS
	Deng Xiaodong, 2018	Acupuncture, qd+RT	RT	3 weeks/NR	TER, FMA
	Du Xin, 2018	Acupuncture, qd+RT3	RT3	4 weeks/NR	TER, FMA, BI
	Feng Shengwang, 2016	Acupuncture, qd+RT4	RT4	3 weeks/NR	TER, VFSS
	Fu Qinhui, 2016	Acupuncture, qd+RT	RT	8 weeks/NR	FMA, BI
	Fu Xiaofeng,2019	Acupuncture, qd+RT	RT	4 weeks/NR	TER, FMA, BI
	Gao Ting, 2018	Acupuncture, qd+RT5	RT5	4 weeks/NR	TER, FMA, BI, BFGF, VEGF
	Huang Wei, 2018	Acupuncture, qd+RT	RT	4 weeks/NR	TER
	Jiang Ming, 2018	Acupuncture, qd+RT6	RT6	4 weeks/NR	TER, FMA, ADL, NIHSS
	Lin Biyu, 2018	Acupuncture, qd+RT7	RT7	20 days/NR	TER, BI
	Liu Sang, 2018	Acupuncture, qd+RT	RT	2 weeks/NR	TER, FMA, BI
	Peng Shaokun, 2015	Acupuncture, qd+RT	RT	3 weeks/NR	TER, BI
	Shi Youjia, 2018	Acupuncture, qd+RT	RT	NR/NR	ADL, NIHSS
	Shi Yunhua, 2017	Acupuncture, qod+RT	RT	4 weeks/NR	TER
	Song Yi, 2017	Acupuncture, qd+RT8	RT8	4 weeks/5 months	FMA, NIHSS
	Tang Youbin, 2014	Acupuncture, qd+RT	RT	NR/NR	TER, ADL
	Wang Jing, 2019	Acupuncture, qd+RT9	RT9	12 weeks/3 months	ADL
	Xiao Yu, 2013	Acupuncture, qd+RT	RT	12 weeks/NR	TER
	Xie Xiaojuan, 2018	Acupuncture, qd+RT	RT	4 weeks/NR	TER, NIHSS
	Xu Lei, 2017	Acupuncture, qd+RT	RT	40 days/NR	TER, FMA, BI
	Xu Wansong, 2017	Acupuncture, qd+RT	RT	40 days/NR	TER, FMA, BI, NIHSS
	Zhang Liao, 2018	Acupuncture, qd+RT10	RT10	10 weeks/NR	FMA, BI, NIHSS
	Zhang Ningxia, 2010	Acupuncture, qd+RT11	RT11	3 weeks/NR	TER, FMA, BI, NIHSS
	Zhou Minya, 2016	Acupuncture, qd+RT	RT	4 weeks/NR	TER, BI
	Zhou Shuxin, 2018	Acupuncture, qd+RT12	RT12	4 weeks/NR	IgA, IgG, IgM

OTTCM	Yao Baonong, 2014	Moxibustion+RT	RT	1 month/NR	Bl
	Zhu Xiaolei, 2017	Needle knife+RT	RT	4 weeks/NR	FMA
	Yan Jiang, 2017	SSIEAC+RT	RT	15 days/NR	NIHSS, TER
	Qi Jiangmin, 2017	Moxibustion+RT	RT	1 week/NR	FMA, TER
	Huo and Wang, 2014	Moxibustion+RT	RT	20 days/1 month	FMA, Barthel
	Guo Chenggang, 2015	Needle knife+RT	RT	6 weeks/NR	FMA, Barthel
	Ding Min, 2018	Needle knife+RT	RT	15 days/NR	FMA, CSI, TER
	Yan Hongda, 2018	Moxibustion+RT	RT	8 weeks/NR	MOCA, Barthel, FMA
	Zhao Lijuan, 2013	SWM+RT	RT	15 days/NR	FMA, Barthel
	Nie Bin, 2013	Moxibustion+RT	RT	2 months/NR	FMA, Barthel, TER
	Hou and Liu, 2014	Moxibustion+RT	RT	20 days/1 month	FMA, Barthel
	Huo Xinhui, 2016	Moxibustion+RT	RT	1 month/1 month	FMA
	Yang Haixia, 2016	Moxibustion+RT	RT	1 month/NR	MRS
	Li Chaoming, 2018	Moxibustion+RT	RT	4 weeks/NR	Barthel, MRS, TER
	Zhao Yang, 2017	Moxibustion+RT	RT	2 months/NR	NIHSS, TER
	Wang Ling, 2014	Moxibustion+RT	RT	3 weeks/NR	FMA

ADL: evaluation result of activities of daily living; bid: twice a day; BI: Barthel Index; BFGF: serum fibrillar growth factor; CSI: clinical spasticity index; FMA: Fugl-Meyer Assessment; FIB: fibrinogen; hs-CRP: hypersensitive C-reactive protein; HDL: high-density lipoprotein; HCY: homocysteine; HCT: hematocrit; ivdrip: intravenous drip; IgA: immunoglobulin A; IgG: Immunoglobulin G; IgM: immunoglobulin M; LDL: low-density lipoprotein; MRS: modified Rankin scale; NIHSS: National Institutes of Health Stroke Scale; po: oral administration; PV: plasma viscosity; qd: once a day; RT: routine treatment; SITCM: syndrome integral of traditional Chinese medicine; SSA: standardized swallowing assessment; SSIEAC: self-made square internal and external application combined with puncture and cupping; SWM: scrapping with moxibustion; TER: total efficacy rate; TC: total cholesterol; TG: triglyceride; tid: three times a day; VEGF: vascular endothelial growth factor; VFSS: videofluoroscopy swallowing study; WHV: whole high viscosity; WLV: whole low viscosity.