Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19

Table 3

Multivariable analyses of the risk factors for intensive care in patients with mild COVID-19.

	Unadjusted			Model 1			Model 2			Model 3
	OR	95% CI		OR	95% CI		OR	95% CI		OR	95% CI
With CV conditions	6.545	3.357-12.762	0.001	6.430	3.210-12.878	<0.001	3.941	1.798-8.636	0.001	2.652	1.019-6.899	0.046
Age	1.006	0.983-1.030	0.604	0.994	0.969-1.020	0.647	0.993	0.966-1.020	0.601	0.991	0.961-1.021	0.545
Sex	1.402	0.792-2.480	0.246	1.284	0.699-2.359	0.007	1.384	0.720-2.663	0.330	0.960	0.447-2.062	0.916
Chest tightness	6.044	2.788-13.107	0.001				3.451	1.422-8.376	0.006	3.340	1.070-10.429	0.038
Diabetes mellitus	2.825	0.799-9.987	0.107				2.473	0.606-10.087	0.207	2.784	0.604-12.826	0.189
Lung diseases	3.682	0.801-16.915	0.094				3.604	0.557-23.327	0.178	3.806	0.480-30.183	0.206
Platelet	0.991	0.986-0.996	<0.001							0.233	0.075-0.726	0.012
Radiologic abnormality	0.238	0.125-0.451	0.001							0.218	0.101-0.468	0.001
Positive SARS-CoV-2 testing by RT-PCR ≥ 2	4.135	2.187-7.817	0.001							3.754	1.719-8.197	0.001

Sample size: . Data are expressed as (reported in parentheses) as assessed by univariate (unadjusted) or multivariate logistic regression analyses. OR: odds ratio; CI: confidence interval; CV: cardiovascular. In these logistic regression models, CV condition was a categorical variable. Other covariates included in multivariate logistic regression models were as follows: model 1: adjustment for age and sex; model 2: adjustment for variables including age, sex, chest tightness, diabetes mellitus, and lung diseases; model 3: adjustment for variables including age, sex, chest tightness, diabetes mellitus, lung diseases, platelet, radiologic abnormality, and positive SARS-CoV-2 testing by RT-PCR.