Research Article

Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention

Table 1

Demographic and clinical characteristics of patients with and without thrombocytopenia.

VariableWith TCP ()Without TCP () value

Mean age (yrs)<0.001
Male, (%)758 (81.0)6614 (77.0)0.005
Platelet (×109/L)85 (74–94)174 (141–215)<0.001
Creatinine (μmol/L)85 (72–103)81 (69–95)<0.001
Total bilirubin (μmol/L)13.1 (9.8–17.2)10.9 (8.0–14.8)<0.001
Hypertension, (%)514 (54.9)4949 (57.6)0.12
Diabetes mellitus, (%)273 (29.2)2409 (28.0)0.46
Atrial fibrillation, (%)54 (5.8)332 (3.9)0.005
Hyperlipidemia, (%)68 (7.2)714 (8.3)0.27
Chronic kidney disease, (%)55 (5.9)316 (3.7)0.001
Chronic liver disease, (%)18 (1.9)44 (0.5)<0.001
Unstable angina, (%)265 (28.3)2330 (27.1)0.43
NSTEMI, (%)92 (9.8)813 (9.5)0.71
STEMI, (%)140 (15.0)1445 (16.8)0.15
Cardiogenic shock, (%)23 (2.5)145 (1.7)0.09
Congestive heart failure, (%)112 (12.0)856 (10.0)0.054
Prior cerebrovascular accident, (%)21 (2.2)234 (2.8)0.39
Prior PCI, (%)125 (13.4)1124 (13.1)0.81
Prior CABG, (%)8 (0.9)53 (0.6)0.39
IABP, (%)53 (5.7)397 (4.6)0.15
Stents placed (≥2), (%)278 (29.7)2329 (27.1)0.09
Arterial approach0.27
 Radial, (%)843 (90.1)7844 (91.3)
 Femoral, (%)47 (5.0)407 (4.7)
 Both, (%)36 (3.8)237 (2.8)
 Other, (%)10 (1.1)107 (1.2)
Periprocedural medicine
 Aspirin, (%)903 (96.5)8449 (98.3)<0.001
 Clopidogrel, (%)907 (96.9)8321 (96.8)0.88
 Ticagrelor, (%)41 (4.4)410 (4.8)0.59
 Warfarin, (%)12 (1.3)116 (1.3)0.87
 NOAC, (%)3 (0.3)27 (0.3)1.0
 Tirofiban, (%)161 (17.2)1531 (17.8)0.64
 Enoxaparin, (%)254 (27.1)2448 (28.5)0.39

TCP: thrombocytopenia; LDL-C: low-density lipoprotein cholesterol; NSTEMI: non-ST-segment elevation myocardial infarction; STEMI: ST-segment elevation myocardial infarction; PCI: percutaneous coronary intervention; CABG: coronary artery bypass graft; IABP: intra-aortic balloon pump; NOAC: new oral anticoagulants.