Deficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in Mice

Table 5

The Cox’s model parameters for different subgroups of PARP-1^+/+ and PARP-1^−/− mice.

Hazard PARP-1^−/− versus PARP-1^+/+	B	exp (β)	se (β)	p
All mice	0.83	2.3	0.18	2.10e-06
Mice with tumors	0.91	2.47	0.21	1.50e-05
Mice with fatal tumors	0.93	2.54	0.24	9.40e-05
Mice with nonfatal tumors	0.97	2.65	0.27	3.90e-04