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Current Gerontology and Geriatrics Research
Volume 2011, Article ID 175763, 7 pages
Clinical Study

Sex-Specific Gait Patterns of Older Adults with Knee Osteoarthritis: Results from the Baltimore Longitudinal Study of Aging

1Clinical Research Branch, (NIA/NIH), Harbor Hospital, 3001 S. Hanover Street, Baltimore, MD 21225, USA
2Department of Mechanical Engineering, Chonnam National University (CNU), Yeosu 550-749, Republic of Korea

Received 30 November 2010; Revised 15 February 2011; Accepted 28 February 2011

Academic Editor: A. Viidik

Copyright © 2011 Seung-uk Ko et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Men and women exhibit different gait patterns during customary walking and may respond differently to joint diseases. The present paper aims to identify gait patterns associated with knee-OA separately in men and women. Participants included 144 men and 124 women aged 60 years and older enrolled in the Baltimore Longitudinal Study of Aging (BLSA) who underwent gait testing at a self-selected speed. Both men and women with knee-OA had lower ankle propulsion mechanical work expenditure (MWE; 𝑃 < . 0 0 1 for both) and higher hip generative MWE ( 𝑃 < . 0 0 1 ) compared to non-OA controls. Women with knee-OA had a higher BMI ( 𝑃 = . 0 0 8 ), slower gait speed ( 𝑃 = . 0 4 9 ), and higher knee frontal-plane absorbing MWE ( 𝑃 = . 0 0 7 ) than women without knee-OA. These differences were not observed in men. Understanding sex-specific differences in gait adaptation to knee-OA may inform the development of appropriate strategies for early detection and intervention for knee-OA in men and women.