Research Article

The Effects of Old Age on Hepatic Stellate Cells

Table 1

Transmission electron microscopic analyses of the effects of old age on HSC.

Number of lipid droplets/HSCNumber of lipid droplets/HSC with nucleusDiameter of lipid droplets in HSC (μm2)HSC protruding into sinusoidal lumen (number and % of total HSC)

Rats
 Young 6 . 7 6 ± 4 . 5 1 6 . 9 1 ± 4 . 5 9 1 . 0 8 ± 0 . 4 4 8 (7%)
 Old 9 . 1 7 ± 6 . 3 5 * 1 0 . 0 9 ± 6 . 3 8 * 1 . 2 0 ± 0 . 5 0 * 10 (10%)
Mice
 Young 2 . 4 1 ± 1 . 2 4 2 . 4 1 ± 1 . 2 4 1 . 8 3 ± 0 . 8 7 3 (5%)
 Old 6 . 3 3 ± 3 . 5 5 * 6 . 7 7 ± 4 . 3 1 * 3 . 1 5 ± 2 . 1 9 * 29 (51%)*

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