Polymorphisms in HSD17B1: Early Onset and Increased Risk of Alzheimer’s Disease in Women with Down Syndrome

Table 1

Demographic characteristics.

Characteristic	Nondemented	Alzheimer's disease
𝑁	164	74
Age at baseline (M, SD)**	47.3 ± 6.9	54.2 ± 6.7
Level of intellectual disability (𝑛, %)
Mild/moderate	97 (59.1)	35 (47.3)
Severe/profound	67 (40.9)	39 (52.7)
Ethnicity (𝑛, %)
Non-hispanic white	142 (86.6)	68 (91.9)
Nonwhite	22 (13.4)	6 (8.1)
Body mass index (M, SD)**	29.9 ± 6.7	28.0 ± 6.0
Apolipoprotein E ε4 allele (𝑛, %)	34 (21.0)	20 (27.0)

** 𝑃<0.05.