Current Gerontology and Geriatrics Research

Mechanisms and Implications of Age-Related Changes in the Liver


Publishing date
01 Jul 2011
Status
Published
Submission deadline
01 Jan 2011

Lead Editor

1Centre for Education and Research on Ageing and ANZAC Research Institute, University of Sydney, Concord, NSW 2139, Australia

2Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital and University of Sydney, St Leonards, NSW 2065, Australia

3Department of Cell Biology and Histology, University of Tromsø, 9037 Tromsø, Norway


Mechanisms and Implications of Age-Related Changes in the Liver

Description

Despite the fact that aging is the major independent risk factor for most diseases, there is almost no understanding of how old age predisposes to disease. The age-related decrease in liver function is substantial and very relevant for systemic exposure to substrates implicated in disease pathogenesis and aging.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the underlying mechanisms and implications of age-related changes in the liver, the development of strategies to attenuate and overcome these conditions, and the evaluation of outcomes. Potential topics include, but are not limited to:

  • Changes to the hepatic sinusoid in aging
  • Aging, cancer, and the liver
  • Changes in drug toxicity in aging
  • Complexity of hepatic drug metabolism in old age
  • The liver and aging: implications for immune diseases
  • Caloric restriction and the aging liver

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/cggr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 150364
  • - Editorial

Mechanisms and Implications of Age-Related Changes in the Liver

Victoria C. Cogger | Sarah N. Hilmer | Dmitri Svistounov
  • Special Issue
  • - Volume 2011
  • - Article ID 831536
  • - Review Article

Mechanisms and Implications of Age-Related Changes in the Liver: Nonalcoholic Fatty Liver Disease in the Elderly

Lay Gan | Shivakumar Chitturi | Geoffrey C. Farrell
  • Special Issue
  • - Volume 2011
  • - Article ID 526379
  • - Review Article

Liver Regeneration and Aging: A Current Perspective

Douglas L. Schmucker | Henry Sanchez
  • Special Issue
  • - Volume 2011
  • - Article ID 628670
  • - Review Article

Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer

Xiaoye He | Stephen J. Clarke | Andrew J. McLachlan
  • Special Issue
  • - Volume 2011
  • - Article ID 624156
  • - Review Article

Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol

Sarah J. Mitchell | Alice E. Kane | Sarah N. Hilmer
  • Special Issue
  • - Volume 2011
  • - Article ID 439835
  • - Research Article

The Effects of Old Age on Hepatic Stellate Cells

Alessandra Warren | Victoria C. Cogger | ... | David G. Le Couteur
  • Special Issue
  • - Volume 2011
  • - Article ID 859415
  • - Review Article

Metabolism, Genomics, and DNA Repair in the Mouse Aging Liver

Michel Lebel | Nadja C. de Souza-Pinto | Vilhelm A. Bohr
Current Gerontology and Geriatrics Research
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