Table of Contents
Chemotherapy Research and Practice
Volume 2011 (2011), Article ID 175054, 9 pages
http://dx.doi.org/10.1155/2011/175054
Research Article

Cisplatin Tumor Biodistribution and Efficacy after Intratumoral Injection of a Biodegradable Extended Release Implant

1Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University of Jerusalem, 91120 Jerusalem, Israel
2Department of Urology, Hadassah Medical Center, 91120 Jerusalem, Israel
3Department of Microbiology and Molecular Genetics, The Kuvin Centre for the Study of Infectious and Tropical Diseases, Hadassah Medical School—Faculty of Medicine, The Hebrew University of Jerusalem, 91120 Jerusalem, Israel

Received 1 September 2010; Revised 26 November 2010; Accepted 11 January 2011

Academic Editor: Elias Jabbour

Copyright © 2011 Ariella Shikanov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. A. Walter, R. J. Tamargo, A. Olivi et al., “Intratumoral chemotherapy,” Neurosurgery, vol. 37, no. 6, pp. 1129–1145, 1995. View at Google Scholar · View at Scopus
  2. D. H. Moore, “Chemotherapy for recurrent cervical carcinoma,” Current Opinion in Oncology, vol. 18, no. 5, pp. 516–519, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. C. A. Rabik and M. E. Dolan, “Molecular mechanisms of resistance and toxicity associated with platinating agents,” Cancer Treatment Reviews, vol. 33, no. 1, pp. 9–23, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. C. N. Sternberg, S. M. Donat, J. Bellmunt et al., “Chemotherapy for bladder cancer: treatment guidelines for neoadjuvant chemotherapy, bladder preservation, adjuvant chemotherapy, and metastatic cancer,” Urology, vol. 69, no. 1, pp. 62–79, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Ramachandran, A. P. Quist, S. Kumar, and R. Lal, “Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity,” Langmuir, vol. 22, no. 19, pp. 8156–8162, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Uchino, Y. Matsumura, T. Negishi et al., “Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats,” British Journal of Cancer, vol. 93, no. 6, pp. 678–687, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Konishi, Y. Tabata, M. Kariya et al., “In vivo anti-tumor effect through the controlled release of cisplatin from biodegradable gelatin hydrogel,” Journal of Controlled Release, vol. 92, no. 3, pp. 301–313, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. F. A. Chen, M. A. Kuriakose, M. X. Zhou, M. D. DeLacure, and R. L. Dunn, “Biodegradable polymer-mediated intratumoral delivery of cisplatin for treatment of human head and neck squamous cell carcinoma in a chimeric mouse model,” Head and Neck, vol. 25, no. 7, pp. 554–560, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. D. T. T. Yapp, D. K. Lloyd, J. Zhu, and S. M. Lehnert, “Cisplatin delivery by biodegradable polymer implant is superior to systemic delivery by osmotic pump or i.p. injection in tumor-bearing mice,” Anti-Cancer Drugs, vol. 9, no. 9, pp. 791–796, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. S. K. Dordunoo, A. M. C. Oktaba, W. Hunter, W. Min, T. Cruz, and H. M. Burt, “Release of taxol from poly(ε-caprolactone) pastes: effect of water-soluble additives,” Journal of Controlled Release, vol. 44, no. 1, pp. 87–94, 1997. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Langer, “Biomaterials in drug delivery and tissue engineering: one laboratory's experience,” Accounts of Chemical Research, vol. 33, no. 2, pp. 94–101, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. D. Teomim and A. J. Domb, “Fatty acid terminated polyanhydrides,” Journal of Polymer Science, Part A: Polymer Chemistry, vol. 37, no. 16, pp. 3337–3344, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Teomim, A. Nyska, and A. J. Domb, “Ricinoleic acid-based biopolymers,” Journal of Biomedical Materials Research, vol. 45, no. 3, pp. 258–267, 1999. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Hakkarainen, “Aliphatic polyesters: abiotic and biotic degradation and degradation products,” Advances in Polymer Science, vol. 157, pp. 113–138, 2002. View at Google Scholar · View at Scopus
  15. D. S. Katti, S. Lakshmi, R. Langer, and C. T. Laurencin, “Toxicity, biodegradation and elimination of polyanhydrides,” Advanced Drug Delivery Reviews, vol. 54, no. 7, pp. 933–961, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Vaisman, M. Motiei, A. Nyska, and A. J. Domb, “Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats,” Journal of Biomedical Materials Research Part A, vol. 92, no. 2, pp. 419–431, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Y. Krasko, A. Shikanov, A. Ezra, and A. J. Domb, “Poly(ester anhydride)s prepared by the insertion of ricinoleic acid into poly(sebacic acid),” Journal of Polymer Science, Part A: Polymer Chemistry, vol. 41, no. 8, pp. 1059–1069, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Shikanov and A. Domb, “Poly(sebacic acid-co-ricinoleic acid) biodegradable injectable in situ gelling polymer,” Biomacromolecules, vol. 7, no. 1, pp. 288–296, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Elkin, S. Ayesh, T. Schneider, N. De Groot, A. Hochberg, and I. Ariel, “The dynamics of the imprinted H19 gene expression in the mouse model of bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl)nitrosamine,” Carcinogenesis, vol. 19, no. 12, pp. 2095–2099, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. S. Soncin, V. L. Cicero, G. Astori et al., “A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice,” Journal of Translational Medicine, vol. 7, pp. 1–9, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. E. S. Y. Chan, A. R. Patel, A. K. Smith et al., “Optimizing Orthotopic Bladder Tumor Implantation in a Syngeneic Mouse Model,” Journal of Urology, vol. 182, no. 6, pp. 2926–2931, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. I. Yudovin-Farber, N. Beyth, A. Nyska, E. I. Weiss, J. Golenser, and A. J. Domb, “Surface characterization and biocompatibility of restorative resin containing nanoparticles,” Biomacromolecules, vol. 9, no. 11, pp. 3044–3050, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. W. C. Zamboni, A. C. Gervais, M. J. Egorin et al., “isposition of platinum (Pt) in B16 murine melanoma tumors after administration of cisplatin or pegylated liposomal-cisplatin formulations (SPI-077 and SPI-077B103),” Clinical Cancer Research, vol. 6, no. 132, 2000. View at Google Scholar
  24. W. C. Zamboni, A. C. Gervais, M. J. Egorin et al., “Inter-and intratumoral disposition of platinum in solid tumors after administration of cisplatin,” Clinical Cancer Research, vol. 8, no. 9, pp. 2992–2999, 2002. View at Google Scholar
  25. H. J. Kuh, S. H. Jang, M. G. Wientjes, J. R. Weaver, and J. L. S. Au, “Determinants of paclitaxel penetration and accumulation in human solid tumor,” Journal of Pharmacology and Experimental Therapeutics, vol. 290, no. 2, pp. 871–880, 1999. View at Google Scholar · View at Scopus
  26. T. J. Vogl, K. Engelmann, M. G. Mack et al., “CT-guided intratumoural administration of cisplatin/epinephrine gel for treatment of malignant liver tumours,” British Journal of Cancer, vol. 86, no. 4, pp. 524–529, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. T. P. F. Gade, I. M. Buchanan, M. W. Motley, Y. Mazaheri, W. M. Spees, and J. A. Koutcher, “Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors,” Clinical Cancer Research, vol. 15, no. 1, pp. 247–255, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. W. C. Zamboni, A. C. Gervais, M. J. Egorin et al., “Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma,” Cancer Chemotherapy and Pharmacology, vol. 53, no. 4, pp. 329–336, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. A. Shikanov, S. Shikanov, B. Vaisman, J. Golenser, and A. J. Domb, “Paclitaxel tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant,” International Journal of Pharmaceutics, vol. 358, no. 1-2, pp. 114–120, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Shikanov, A. Shikanov, O. Gofrit, A. Nyska, B. Corn, and A. J. Domb, “Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer,” Journal of Pharmaceutical Sciences, vol. 98, no. 3, pp. 1005–1014, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Nagai and Y. Sumino, “Therapeutic strategy of advanced hepatocellular carcinoma by using combined intra-arterial chemotherapy,” Recent Patents on Anti-Cancer Drug Discovery, vol. 3, no. 3, pp. 220–226, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. V. R. Recinos, B. M. Tyler, K. Bekelis et al., “Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model,” Neurosurgery, vol. 66, no. 3, pp. 530–537, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. S. I. Sugiyama, Y. Yamashita, T. Kikuchi, Y. Sonoda, T. Kumabe, and T. Tominaga, “Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts,” Neurological Research, vol. 30, no. 9, pp. 960–967, 2008. View at Publisher · View at Google Scholar · View at Scopus